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  • Probiotics | Microbial Species | Indogulf BioA

    Lactobacillus fermentum aids in digestion, supports immune health, and has antioxidant properties that benefit gut health and overall well-being. < Microbial Species Lactobacillus fermentum Lactobacillus fermentum aids in digestion, supports immune health, and has antioxidant properties that benefit gut health and overall well-being. Strength 1 x 10⁸ CFU per gram / 1 x 10⁹ CFU per gram Product Enquiry Download Brochure Benefits Support for Lactose Digestion It assists in the breakdown of lactose, making it beneficial for those with lactose intolerance. Digestive Health Improvement This probiotic supports digestive health by promoting a balanced gut microbiota and alleviating symptoms of gastrointestinal discomfort. Immune System Support It enhances immune function by stimulating the production of immune cells and helping the body combat infections. Antioxidant Properties This strain exhibits antioxidant effects, helping to reduce oxidative stress and inflammation in the body. Dosage & Application Additional Info Scientific References Mode of Action FAQ Scientific References Content coming soon! Mode of Action Content coming soon! Additional Info Key Features All microbial strains are characterized using 16S rDNA. All products are non-GMO. No animal-derived materials are used. The typical shelf life is 2 years. All strains are screened in-house using high-throughput screening methods. We can customize manufacturing based on the required strength and dosage. High-resilience strains Stable under a wide pH range Stable under a broad temperature range Stable in the presence of bile salts and acids Do not show antibiotic resistance Packaging Material The product is packaged in a multi-layer, ultra-high barrier foil that is heat-sealed and placed inside a cardboard shipper or plastic drum. Shipping Shipping is available worldwide. Probiotic packages are typically transported in insulated Styrofoam shippers with dry ice to avoid exposure to extreme high temperatures during transit. Support Documentation Certificate of Analysis (COA) Specifications Material Safety Data Sheets (MSDS) Stability studies (18 months) Certifications ISO 9001 ISO 22000 HACCP Halal and Kosher Certification (for Lactobacillus strains) FSSAI Dosage & Application Contact us for more details FAQ Content coming soon! Related Products Bifidobacterium animalis Bifidobacterium bifidum Bifidobacterium breve Bifidobacterium infantis Bifidobacterium longum Clostridium butyricum Lactobacillus acidophilus Lactobacillus bulgaricus More Products Resources Read all

  • Paenibacillus Azotofixans Manufacturer & Exporter | Nitrogen Fixing Bacteria | Microbial Species | Indogulf BioA

    Paenibacillus azotofixans: Utilized in agricultural practices to promote plant growth by fixing atmospheric nitrogen, thus improving soil fertility, especially in various crop fields. < Microbial Species Paenibacillus azotofixans Paenibacillus azotofixans: Utilized in agricultural practices to promote plant growth by fixing atmospheric nitrogen, thus improving soil fertility, especially in various crop fields. Strength 1 x 10⁸ CFU per gram / 1 x 10⁹ CFU per gram Product Enquiry Download Brochure Benefits Nitrogen Fixation Paenibacillus azotofixans fixes atmospheric nitrogen into ammonia, which enhances nitrogen availability for plants, supporting their growth and development. Plant Growth Promotion Paenibacillus azotofixans produces phytohormones like auxins and cytokinins, which stimulate root growth and increase the efficiency of nutrient and water uptake. Disease Suppression It exhibits antagonistic activity against various plant pathogens, helping to suppress diseases and enhance plant health through competition and antibiotic production. Phosphate Solubilization It solubilizes phosphate in the soil, making it more accessible to plants, which improves their phosphorus uptake and overall nutrient status. Dosage & Application Additional Info Scientific References Mode of Action FAQ Scientific References Molecular Biology and Genetics Genome-Scale Studies: Comprehensive transcriptome analysis of nitrogen fixation in Paenibacillus species has identified over 9,000 differentially expressed genes involved in nitrogen metabolism, energy production, and stress response. These studies provide detailed insights into the molecular mechanisms underlying nitrogen fixation efficiency. biomedcentral Phylogenetic Analysis: Molecular phylogenetic studies based on nifH gene sequences demonstrate that Paenibacillus azotofixans nitrogen-fixing genes cluster with cyanobacterial and archaeal nitrogenases, suggesting ancient evolutionary origins and potential for high activity. journals.asm Regulatory Mechanisms: Advanced molecular studies have elucidated complex regulatory networks involving GlnR, AdeR, and other transcriptional regulators that control nitrogen fixation in response to environmental conditions. microbialcellfactories.biomedcentral+1 Field Performance and Agricultural Applications Multi-Location Trials: Extensive field trials across different climatic zones and soil types consistently demonstrate the effectiveness of Paenibacillus azotofixans for enhancing crop productivity. These studies provide robust evidence for the bacterium's agricultural value under diverse conditions. pmc.ncbi.nlm.nih+1 Long-Term Sustainability: Research demonstrates that repeated application of Paenibacillus azotofixans maintains soil health and fertility without negative environmental impacts. Long-term studies show sustained benefits over multiple growing seasons. pmc.ncbi.nlm.nih Economic Analysis: Cost-benefit analyses demonstrate positive returns on investment from Paenibacillus azotofixans applications, with reduced fertilizer costs offsetting inoculation expenses while providing additional yield benefits. cropj Mode of Action Nitrogen Fixation Biochemistry Paenibacillus azotofixans employs a highly regulated nitrogenase system consisting of multiple enzyme complexes that work together to reduce atmospheric nitrogen: journals.asm+1 Oxygen Sensitivity Management: As an obligate anaerobe process, nitrogen fixation by nitrogenase requires oxygen-free conditions. Paenibacillus azotofixans creates localized anaerobic microenvironments through rapid oxygen consumption and biofilm formation. biomedcentral Energy Requirements: The nitrogen fixation process requires substantial ATP input (16 molecules of ATP per molecule of N₂ fixed). Paenibacillus azotofixans meets this energy demand through efficient carbohydrate metabolism and optimized electron transport chains. biomedcentral Metal Cofactor Utilization: The nitrogenase enzyme complex requires molybdenum, iron, and sulfur cofactors. Paenibacillus azotofixans possesses specialized transport systems for acquiring and concentrating these essential metals. biomedcentral Metabolic Integration and Regulation Ammonium Tolerance Mechanisms: Recent research has revealed that certain Paenibacillus species can overcome ammonium inhibition of nitrogen fixation through alanine dehydrogenase (ADH) activity. This mechanism allows continued nitrogen fixation even in soils with moderate nitrogen availability. microbialcellfactories.biomedcentral Carbon-Nitrogen Balance: The bacterium maintains optimal carbon-nitrogen ratios through sophisticated regulatory networks that coordinate nitrogen fixation with carbon metabolism. This integration ensures efficient resource utilization and sustained bacterial activity. journals.asm Stress Response Systems: Paenibacillus azotofixans possesses multiple stress response mechanisms that maintain nitrogen fixation activity under challenging environmental conditions including drought, temperature extremes, and pH variations. microbialcellfactories.biomedcentral Applications in Biofertilizers and Soil Health Management Commercial Biofertilizer Formulations Paenibacillus azotofixans serves as a key component in advanced biofertilizer formulations designed for various agricultural applications: indogulfbioag+1 Multi-Strain Consortiums: Commercial products often combine Paenibacillus azotofixans with complementary bacteria such as phosphorus-solubilizing bacteria and biocontrol agents to provide comprehensive plant nutrition and protection. indogulfbioag Crop-Specific Formulations: Different application methods and strain combinations are optimized for specific crops and growing conditions. Soybean formulations may emphasize nitrogen fixation, while vegetable applications focus on rapid establishment and growth promotion. cropj Delivery Systems: Paenibacillus azotofixans can be formulated for seed treatment, soil application, or irrigation system delivery, providing flexibility for different farming operations. indogulfbioag Integration with Sustainable Farming Practices Organic Agriculture: As a naturally occurring, non-GMO bacterium, Paenibacillus azotofixans is approved for organic farming systems and supports organic certification requirements. indogulfbioag Precision Agriculture: The bacterium can be integrated into precision farming systems where GPS-guided application ensures optimal placement and dosing based on field-specific soil conditions and crop requirements. Conservation Agriculture: Paenibacillus azotofixans supports no-till and reduced-tillage farming systems by maintaining soil biological activity and nitrogen availability without mechanical soil disturbance. Paenibacillus Species Diversity and Agricultural Significance The Broader Paenibacillus Genus The Paenibacillus species represent one of the most diverse bacterial genera in soil ecosystems, with over 211 described species exhibiting remarkable genetic and phenotypic diversity. This diversity reflects extensive horizontal gene transfer and adaptive evolution that has enabled Paenibacillus species to colonize diverse environmental niches. pmc.ncbi.nlm.nih+1 Genomic Diversity: Comparative genomic analyses reveal that Paenibacillus species possess highly variable genome sizes ranging from 3.9 to 10.4 megabases, with extensive variation in gene content even within species. This genomic plasticity underlies the genus's exceptional environmental adaptability. nature Metabolic Versatility: Paenibacillus species demonstrate remarkable metabolic diversity, with different species specialized for various functions including nitrogen fixation, phosphate solubilization, biocontrol, and organic matter decomposition. This metabolic diversity makes them valuable for diverse agricultural applications. nature Nitrogen-Fixing Paenibacillus Species Multiple Paenibacillus species possess nitrogen-fixing capabilities, each adapted to specific environmental conditions and plant associations: frontiersin+1 Paenibacillus polymyxa: Perhaps the most extensively studied species, demonstrating nitrogen fixation, biocontrol activity, and plant growth promotion across numerous crop species. pmc.ncbi.nlm.nih+1 Paenibacillus borealis: Isolated from forest humus, this species contributes to nitrogen cycling in forest ecosystems and demonstrates potential for forestry applications. microbiologyresearch Paenibacillus graminis: Associated with grass rhizospheres, this species enhances nitrogen availability in forage and turf systems. frontiersin Additional Info Incomplete Section Finalization Paenibacillus azotofixans is recognized for its agricultural significance as a potent nitrogen fixer and plant growth promoter. Modern molecular biology and field-scale studies have validated its benefits for crop nutrition, environmental sustainability, and cost-effectiveness. The bacterium’s versatility and resilience are supported by its diverse regulatory, metabolic, and stress response mechanisms, which make it compatible across a wide range of soil conditions and crop systems. Laboratory Contaminant Significance Paenibacillus species are widely distributed in natural and built environments, including soil, water, and air. Their ability to form spores and survive harsh conditions means they are frequent laboratory contaminants. In clinical and research laboratories, Paenibacillus can be isolated from surfaces, air, gloves, and sample materials—often as part of sterility testing. Several species, including Paenibacillus contaminans, have been specifically described as contaminants during laboratory plate handling. This is particularly relevant in low-biomass environments, as modern sequencing or culture approaches can easily detect spores or cells introduced during sample processing or from ambient air. The high occurrence of Paenibacillus as a contaminant can result in false-positive results, especially in blood cultures, sterile fluids, or low-biomass samples. Proper sample collection, rigorous sterilization, and careful interpretation of culture results are imperative. Contaminants are often identified retrospectively by phylogenetic and phenotypic analysis and may comprise the majority of positive cultures unless clear clinical evidence of infection is present. pmc.ncbi.nlm.nih+3 Human Pathogenicity Paenibacillus species are generally regarded as environmental and plant-associated bacteria. However, accumulating evidence shows that a subset can act as opportunistic pathogens in humans—particularly in immunocompromised individuals, neonates, or following traumatic injuries. Human infections are rare but increasingly described in clinical case reports and systematic reviews. Several species implicated in human disease include P. alvei, P. thiaminolyticus, P. lautus, P. provencensis, and others. Infections range from wound infections, abscesses, ocular infections, sepsis, meningitis, and, rarely, endocarditis. Pathogenicity is driven by several factors: Spore formation and environmental resilience: Spores remain viable on skin surfaces and within hospital environments, making transmission and infection possible under specific conditions. d-nb+1 Virulence factors: Some Paenibacillus possess genes for thiol-activated cytolysins, proteases, biofilm formation, and antimicrobial compound production. journals.plos+3 Antibiotic resistance: Many isolates demonstrate resistance to multiple antibiotics, particularly penicillins, clindamycin, sulfonamides, and sometimes vancomycin, calling for careful susceptibility testing. pure.psu+4 Clinical Management Recommendations Management of Paenibacillus infections hinges on accurate diagnosis and effective antimicrobial therapy. As precaution, clinicians should: Differentiate true infection from contamination: Always correlate positive cultures with clinical signs (fever, leukocytosis, infection at the site), especially when Paenibacillus is isolated from blood, sterile fluids, or deep wounds. pmc.ncbi.nlm.nih+2 Empiric and directed antibiotic therapy: Initial therapy is empiric, but due to variable resistance patterns, therapy should be adjusted based on susceptibility testing. Effective options typically include cefotaxime, ceftriaxone, gentamicin, amikacin, rifampicin, metronidazole, and levofloxacin, while resistance to penicillins, clindamycin, and vancomycin can occur. Trimethoprim-sulfamethoxazole may be used for P. urinalis. droracle+6 Remove or drain infection sources: Surgical removal of infected tissues, foreign bodies, or abscess drainage may be necessary in localized infections. Monitor for complications: Especially in infants, Paenibacillus can cause severe complications like meningitis and hydrocephalus, requiring close monitoring and sometimes neurosurgical intervention. thelancet+2 Follow-up and continuity of care: Persistent infections require long-term medical follow-up and sometimes prolonged antibiotic administration. pmc.ncbi.nlm.nih+1 Current Knowledge of Human Infections Systematic reviews and case series demonstrate that although Paenibacillus species are uncommon human pathogens, the number of species associated with clinical infections is growing. Infection presentations differ notably between adults and infants: Adults: Infections are sporadic, caused by a wide array of species, often present as wound infections, abscesses, or localized sepsis. Central nervous system involvement is rare, and most cases resolve with treatment. pubmed.ncbi.nlm.nih+2 Infants: Neonatal infections are far more severe, especially with P. thiaminolyticus, and often present as sepsis or meningitis with a high risk of cerebral destruction and hydrocephalus. Mortality rates are notable, and survivors often need surgical intervention for neurological sequelae. pmc.ncbi.nlm.nih+3 The overall frequency of infection remains low relative to the ubiquity of the genus, indicating that most isolates are contaminants, but vigilance is still warranted for at-risk populations. Recommended Crops: Cereals, Millets, Pulses, Oilseeds, Fibre Crops, Sugar Crops, Forage Crops, Plantation crops, Vegetables, Fruits, Spices, Flowers, Medicinal crops, Aromatic Crops, Orchards, and Ornamentals. Compatibility: Compatible with Bio Pesticides, Bio Fertilizers, and Plant growth hormones but not with chemical fertilizers and chemical pesticides. Shelf Life: Stable within 1 year from the date of manufacturing. Packing: We offer tailor-made packaging as per customers' requirements. Dosage & Application Seed Coating/Seed Treatment: Coat 1 kg of seeds with a slurry mixture of 10 g of Paenibacillus Azotofixans and 10 g of crude sugar in sufficient water. Dry the coated seeds in shade before sowing or broadcasting in the field. Seedling Treatment: Dip seedlings into a mixture of 100 grams of Paenibacillus Azotofixans with sufficient water. Soil Treatment: Mix 3-5 kg per acre of Paenibacillus Azotofixans with organic manure or fertilizers. Incorporate into the soil during planting or sowing. Irrigation: Mix 3 kg per acre of Paenibacillus Azotofixans in water and apply through drip lines. FAQ What is the significance of Paenibacillus as a potential laboratory contaminant? Answer: Paenibacillus species are among the most frequently isolated laboratory contaminants, especially in low-biomass and sterile sample environments. Their spores persist in air, on surfaces, and even on personal protective equipment, leading to inadvertent contamination of cultures and clinical specimens. Laboratory contaminants can cause diagnostic confusion, particularly when isolated from blood cultures or sterile sites, given the genus’s environmental prevalence. Recognizing Paenibacillus as a contaminant is vital to prevent misdiagnosis, unnecessary antimicrobial therapy, and misleading research conclusions. Rigorous sample handling and critical assessment of laboratory results are essential in distinguishing contamination from true infection. sciencedirect+4 Can Paenibacillus species exhibit pathogenicity in humans? Answer: Although primarily environmental and plant-associated, certain Paenibacillus species can exhibit pathogenicity in humans, particularly in vulnerable populations such as neonates, immunocompromised individuals, or following trauma. Documented infections include sepsis, wound infection, abscesses, meningitis, endocarditis, ocular infections, and rare systemic disease. Species like P. alvei, P. thiaminolyticus, and P. lautus are increasingly identified as clinical pathogens. In neonates, P. thiaminolyticus is notably associated with severe CNS infections. Virulence factors, antibiotic resistance, and spore persistence contribute to pathogenic potential, although true infections remain rare compared to environmental contamination. wwwnc.cdc+9 What are the recommended clinical approaches for managing Paenibacillus infections? Answer: Management is guided by accurate diagnosis and susceptibility-directed antimicrobial therapy. Clinicians should distinguish true infection from laboratory contamination, correlate culture results with clinical findings, and employ targeted treatment. Empiric therapy can include cefotaxime, ceftriaxone, gentamicin, amikacin, levofloxacin, and rifampicin, but resistance to penicillin, clindamycin, vancomycin, and sulfonamides is not uncommon. Susceptibility testing is imperative prior to finalizing antibiotic choice. Additional interventions such as surgical drainage of infected tissues may be necessary. Neonatal and CNS infections require close multidisciplinary management. Long-term monitoring is advised due to the potential for persistent or recurrent infection and post-infectious complications. pmc.ncbi.nlm.nih+7 What is currently known about human infections caused by Paenibacillus species? Answer: Human Paenibacillus infections, while uncommon, are increasingly recognized in pediatric and adult populations. Infections in adults are sporadic and generally mild, presenting as localized wound infection, abscesses, or sepsis, and most affected individuals recover without severe sequelae. Neonatal infections, especially those due to P. thiaminolyticus, are severe and often complicated by brain injury, hydrocephalus, and require surgical intervention, with notable associated mortality. The rise in documented cases reflects improved detection, growing awareness, and advances in microbiological diagnostics. Nonetheless, the majority of clinical isolates are contaminants rather than true pathogens, highlighting the importance of careful clinical interpretation and management. Ongoing research is elucidating new species, virulence mechanisms, and optimized treatment protocols. sciencedirect+9 Related Products Acetobacter xylinum Azospirillum brasilense Azospirillum lipoferum Azospirillum spp. Azotobacter vinelandii Beijerinckia indica Bradyrhizobium elkanii Bradyrhizobium japonicum More Products Resources Read all

  • Bioremediation | Microbial Species | Indogulf BioA

    Bacillus macerans is a facultative anaerobic bacterium known for its ability to degrade complex carbohydrates such as cellulose, hemicellulose, and starch. This activity makes it highly effective in organic decomposition processes, such as composting and agricultural residue management, contributing to improved soil health and nutrient cycling. In industrial applications, B. macerans produces valuable enzymes like cellulases and amylases, which are used in biofuel production, paper processing, and textile industries. Its role in breaking down organic polymers also supports bioremediation efforts, helping manage agricultural and industrial waste sustainably.. < Microbial Species Bacillus macerans Bacillus macerans is a facultative anaerobic bacterium known for its ability to degrade complex carbohydrates such as cellulose, hemicellulose, and starch. This activity makes it… Show More Strength 1 x 10⁹ CFU per gram / 1 x 10¹⁰ CFU per gram Product Enquiry Download Brochure Benefits Polysaccharide Degradation Produces enzymes that break down complex polysaccharides, aiding in the decomposition of organic waste. Cellulose Breakdown Efficiently degrades cellulose, contributing to the recycling of plant materials and organic matter. Bioremediation of Wastewater Helps treat industrial and agricultural wastewater by breaking down contaminants. Soil Health Improvement Enhances soil fertility by promoting organic matter decomposition, supporting plant growth and sustainable agriculture. Dosage & Application Additional Info Scientific References Mode of Action FAQ Scientific References Content coming soon! Mode of Action Content coming soon! Additional Info Contact us for more details Dosage & Application Contact us for more details FAQ Content coming soon! Related Products Saccharomyces cerevisiae Bacillus polymyxa Thiobacillus novellus Thiobacillus thiooxidans Alcaligenes denitrificans Bacillus licheniformis Citrobacter braakii Citrobacter freundii More Products Resources Read all

  • Custom Formulation Services for Agriculture | Indogulf BioAg

    Partner with Indogulf BioAg for tailored agri-input solutions. We offer custom formulation services for biofertilizers, biostimulants & micronutrients to match your brand’s needs. Custom Formulation Tailored Microbial Product Design IndoGulf BioAg’s Custom Formulation service develops bespoke microbial solutions adapted to your specific requirements. Contact us Our scientists work closely with you to understand the crop, climate, soil conditions, or target issue at hand – whether it’s a need for a drought-tolerant biofertilizer for arid regions, a specialized microbial blend for a particular crop disease, or a bio-stimulant optimized for greenhouse production. To meet your specific agronomic or environmental goals, we begin by selecting and combining compatible microbial strains along with supporting ingredients. Each component is chosen to work synergistically—whether to boost nutrient uptake, suppress pathogens, or enhance stress tolerance—creating a targeted formulation tailored to your needs. This formulation process is iterative and grounded in data. At the lab scale, we test multiple strain blends and nutrient compositions, evaluating indicators such as plant growth response, metabolite production, and microbial stability. Adjustments to carriers, pH, and nutrient profiles ensure viability during storage and consistent performance during application. We also test for compatibility with standard agricultural practices—verifying that the formulation works seamlessly with fertilizers, pesticides, and various application methods like seed coating, foliar spray, or soil drenching. Once optimized, the prototype is validated through real-world pilot trials. This ensures that your final product is not only scientifically sound but also practical, effective, and uniquely suited to your operational challenges. CRO Services Highlights Targeted Solutions Design of microbial inoculants or consortia for specific crops, soil types, or environmental conditions (for example, saline soil bio-remediation blends or crop-specific probiotic mixes). Formulation R&D Systematic testing of different formulation constituents – including carrier materials, nutrient additives, and encapsulation techniques – to optimize stability and performance. Client Collaboration Interactive development process with your feedback and knowledge incorporated at each stage; we can start from an idea or enhance an existing product concept you have. Confidentiality & IP Security Strict protection of proprietary information – your custom formula remains exclusive to you, with clear agreements on intellectual property ownership for any novel developments. Performance Validation Comprehensive lab and field validation of the final formulation, complete with documentation and samples, so you move forward to commercialization with confidence. Create a microbial product as unique as your needs. Contact our formulation experts to begin developing a custom solution tailored to your crop or project. Contact us

  • Compost Pro Manufacturer & Exporter| Composting Solutions | Environmental Solutions | Indogulf BioAg

    Premier manufacturer & exporter of Compost Pro, offering advanced, eco-friendly compost solutions for sustainable agriculture. < Environmental Solutions Compost Pro Consortium of aerobic microorganisms for fast composting (28-35 days), promoting enzymatic processes and odorless decomposition of organic wastes. Safe and biodegradable. Product Enquiry Download Brochure Benefits Pathogen and Weed Control Destroys pathogens, harmful bacteria, weed seeds, and toxic matter, ensuring safer composting. Enhances Soil Quality Acts as an excellent soil conditioner, enhancing soil quality and structure. Rapid Conversion to Rich Manure Converts all types of organic waste into rich manure rapidly by breaking down the hard structure of the waste. Optimized Decomposition Accelerates the decomposition process to reach a balanced C Composition Dosage & Application Additional Info FAQ Composition Ingredients Percentage Brevivacillus Bacillus Species Bacillus Coagulans Bacillus Licheniformis Bacillus Megaterium Bacillus Subtilis Strptococcus Total Count 6x10₁₁ CFU Actinomycetes - Streptomyces Compost Fungi - Basidiomyces Speices - Trichoderma Species - Myriococcum Thermophilum Total Count 7x10¹¹ CFU per ml Mosphillic Bateria 1.7-2.84 x 10⁹ CFU per ml Dosage & Application Add 1L COMPOST PRO to 100 Kg Organic Waste and mix well. Evenly apply the above mix to one Tonne of Organic Waste to convert all types of organic waste into compost/manure rapidly, Apply water to maintain moisture level on regular basis Additional Info Our application rates are for guidelines only. How to use: Shake the bottle well before use. This product should be mixed with clean water in a plastic container as per the dosage instructions and thoroughly mixed before pouring into organic waste. Instructions to open: Open the bottle outdoors with care. Do not shake the bottle before opening. The bottle has a double seal system - an external black cap and a white inner plug with a nozzle in the center. After opening the black outer cap, pierce the inner plug in the middle using any pointed tool. The nozzle should create a small hole through which the liquid fertilizer can pour out. Usage and storage: Protect from direct sunlight and store in a dark, cool place between 5 to 25°C (40-77°F). Do not refrigerate or freeze. Keep the container tightly sealed after use. Keep away from children and pets. Do not inhale or ingest. FAQ Content coming soon! Related Products Cellulomax Enriched Earth Enzymax More Products Resources Read all

  • Crop Kits | Indogulf BioAg

    < Crop Kits Case Worm Case worms skeletonize rice leaves by feeding within protective cases, reducing photosynthesis. Pest management is essential to minimize damage. Product Enquiry Download Brochure Benefits Composition Dosage & Application Additional Info Dosage & Application Additional Info Related Products Aminomax SP Annomax BioProtek Biocupe Neem Plus Seed Protek Silicomax Dates Pro More Products Resources Read all

  • Probiotics | Microbial Species | Indogulf BioA

    Bacillus amyloliquefaciens, produces plant growth nutrients, suppresses pathogens with enzymes, acts as biofertilizer and biopesticide, improves soil fertility, safe for non-target species and humans. < Microbial Species Streptococcus faecalis Streptococcus faecalis helps maintain a healthy gut microbiome and supports digestive health, promoting overall well-being and vitality. Strength 1 x 10⁸ CFU per gram / 1 x 10⁹ CFU per gram Product Enquiry Download Brochure Benefits Antimicrobial Properties This strain can inhibit the growth of harmful bacteria, contributing to a healthier gut environment and improved gut health. Immune System Enhancement It boosts immune function by stimulating the production of antibodies and enhancing the body’s defenses against infections. Support for Gut Barrier Function It aids in strengthening the gut barrier, reducing intestinal permeability and protecting against pathogens and toxins. Digestive Health Support This probiotic helps maintain a balanced gut microbiota, promoting overall digestive health and alleviating discomfort. Dosage & Application Additional Info Scientific References Mode of Action FAQ Scientific References Content coming soon! Mode of Action Content coming soon! Additional Info Key Features All microbial strains are characterized using 16S rDNA. All products are non-GMO. No animal-derived materials are used. The typical shelf life is 2 years. All strains are screened in-house using high-throughput screening methods. We can customize manufacturing based on the required strength and dosage. High-resilience strains Stable under a wide pH range Stable under a broad temperature range Stable in the presence of bile salts and acids Do not show antibiotic resistance Packaging Material The product is packaged in a multi-layer, ultra-high barrier foil that is heat-sealed and placed inside a cardboard shipper or plastic drum. Shipping Shipping is available worldwide. Probiotic packages are typically transported in insulated Styrofoam shippers with dry ice to avoid exposure to extreme high temperatures during transit. Support Documentation Certificate of Analysis (COA) Specifications Material Safety Data Sheets (MSDS) Stability studies (18 months) Certifications ISO 9001 ISO 22000 HACCP Halal and Kosher Certification (for Lactobacillus strains) FSSAI Dosage & Application Contact us for more details FAQ Content coming soon! Related Products Bifidobacterium animalis Bifidobacterium bifidum Bifidobacterium breve Bifidobacterium infantis Bifidobacterium longum Clostridium butyricum Lactobacillus acidophilus Lactobacillus bulgaricus More Products Resources Read all

  • Bacillus Firmus Manufacturer & Exporter | Phosphorous Solubilizing Bacteria | Microbial Species | Indogulf BioA

    Bacillus firmus enhances phosphorus availability in soil, stimulates root growth, improves fruit quality, and protects against soil-borne diseases. Compatible with bio-pesticides and bio-fertilizers. < Microbial Species Bacillus firmus Bacillus firmus enhances phosphorus availability in soil, stimulates root growth, improves fruit quality, and protects against soil-borne diseases. Compatible with bio-pesticides and bio-fertilizers. Strength 1 x 10⁸ CFU per gram / 1 x 10⁹ CFU per gram Product Enquiry Download Brochure Benefits Enhance Fruit Development and Quality Improves the size, taste, and overall quality of fruits. Increase Sugar Content in Fruits Elevates the sugar levels in fruits, leading to sweeter and more nutritious produce. Protection Against Drought and Diseases Provides resilience against drought conditions and some soil-borne diseases, ensuring healthier plant development. Promote Root Growth Stimulates the development of a robust root system, enhancing nutrient uptake and plant stability. Dosage & Application Additional Info Scientific References Mode of Action FAQ Scientific References 1. Nematode Biocontrol and Root Interaction Bacillus firmus I-1582 effectively degrades nematode eggs, colonizes plant roots, and induces systemic resistance in tomato via salicylic acid (SA) and jasmonic acid (JA) signaling pathways. Ghahremani et al., 2020 – Frontiers in Plant Science Culture filtrates of B. firmus induce paralysis and mortality in nematodes, inhibit egg hatching, and demonstrate antagonistic activity through secondary metabolites. Mendoza et al., 2008 – Biocontrol Science and Technology A split-root study demonstrated both localized and systemic effects of B. firmus GB-126 in suppressing soybean cyst and root-knot nematodes. Schrimsher et al., 2012 – Experimental Study 2. Plant Growth Promotion and Genomic Insights Whole-genome sequencing of strain TNAU1 revealed genes associated with indole-3-acetic acid (IAA) biosynthesis, nutrient solubilization (phosphorus and potassium), nitrate transport, nematicidal proteases, and antibiotic biosynthetic clusters. Settu et al., 2023 – Physiological and Molecular Plant Pathology 3. Enzyme Production and Biotechnological Applications An extracellular nuclease from B. firmus VKPACU-1 displays high specificity for RNA and DNA substrates, indicating potential for biocatalytic and bioremediation applications. Kumar & Kannan, 2011 – Nucleosides, Nucleotides & Nucleic Acids Two xylanases purified from B. firmus exhibit activity over a wide pH range and efficiently degrade xylan to xylo-oligosaccharides, supporting their use in biomass conversion. Tseng et al., 2002 – Enzyme and Microbial Technology 4. Immunomodulatory Properties B. firmus functions as a potent polyclonal B cell activator, enhancing the production of immunoglobulins (notably IgA and IgG) in vitro, with implications for probiotic and adjuvant applications. Prokešová et al., 2008 – Folia Microbiologica Mucosal administration of B. firmus significantly enhanced systemic and mucosal antibody responses to a model antigen in animal models, indicating its potential as a mucosal immunoadjuvant. Mlčková et al., 2001 – Immunology Letters Mode of Action 1. Nematode Control B. firmus produces bioactive secondary metabolites that paralyze and kill nematodes such as Meloidogyne incognita and Radopholus similis . Culture filtrates alone can reduce egg hatching and cause up to 96% mortality in nematode juveniles (Mendoza et al., 2008) , (Settu et al., 2023) . It also degrades nematode eggs directly and colonizes plant roots, creating a physical and chemical barrier against nematode infection (Ghahremani et al., 2020) . 2 . Induction of Plant Resistance In plants like tomato, B. firmus activates systemic resistance by upregulating salicylic acid (SA) and jasmonic acid (JA) pathway genes, helping the plant fight off nematodes and potentially other pathogens (Ghahremani et al., 2020) . These effects can be systemic or localized, depending on the crop and context (Schrimsher et al., 2012) . 3. Plant Growth Promotion Genome analysis reveals genes responsible for: IAA (Indole-3-acetic acid) production (a plant hormone) Phosphorus and potassium solubilization Nitrate transport These contribute to enhanced nutrient uptake and overall plant growth (Settu et al., 2023) . 4. Enzymatic Activity B. firmus secretes nucleases and xylanases, which break down DNA, RNA, and complex polysaccharides—helping degrade organic matter and releasing nutrients in the soil (Kumar & Kannan, 2011) , (Tseng et al., 2002) . 5. Immunomodulatory Effects In animal models, B. firmus stimulates both systemic and mucosal immune responses by increasing the production of immunoglobulins (IgA, IgG) and cytokines (e.g., IFN-γ), making it a candidate as an oral adjuvant or probiotic (Prokešová et al., 2008), (Mlčková et al., 2001). Additional Info Recommended Crops: Cereals, Millets, Pulses, Oilseeds, Fibre Crops, Sugar Crops, Forage Crops, Plantation crops, Vegetables, Fruits, Spices, Flowers, Medicinal crops, Aromatic Crops, Orchards, and Ornamentals. Compatibility: Compatible with Bio Pesticides, Bio Fertilizers, and Plant growth hormones but not with chemical fertilizers and chemical pesticides. Shelf Life: Stable within 1 year from the date of manufacturing. Packing: We offer tailor-made packaging as per customers' requirements. Dosage & Application Seed Coating/Seed Treatment : 1 kg of seeds will be coated with a slurry mixture of 10 g of Bacillus firmus and 10 g of crude sugar in sufficient water. The coated seeds will then be dried in shade and sow or broadcast in the field. Seedling Treatment : Dip the seedlings into the mixture of 100 grams of Bacillus firmus and sufficient amount of water. Soil Treatment : Mix 3-5 kg per acre of Bacillus firmus with organic manure/organic fertilizers. Incorporate the mixture and spread into the field at the time of planting/sowing. Irrigation : Mix 3 kg per acre of Bacillus firmus in a sufficient amount of water and run into the drip lines. FAQ What is Bacillus firmus? Bacillus firmus is a beneficial, spore-forming bacterium widely used in agriculture for biological nematode control and plant growth promotion. It also has potential uses in immunology and biotechnology. How does B. firmus control nematodes? It produces bioactive compounds that paralyze and kill nematodes such as Meloidogyne incognita and Radopholus similis. These compounds also reduce egg hatching and juvenile survival (Mendoza et al., 2008) . Can B. firmus boost plant immunity? Yes. It induces systemic resistance in plants like tomato by activating salicylic acid (SA) and jasmonic acid (JA) signaling pathways, helping plants defend against pests and diseases (Ghahremani et al., 2020) . How does it promote plant growth? B. firmus produces plant growth-promoting substances like indole-3-acetic acid (IAA) and helps solubilize nutrients like phosphorus and potassium, improving nutrient uptake and plant development (Settu et al., 2023) . What enzymes does B. firmus produce? It secretes nucleases that degrade DNA and RNA, and xylanases that break down plant cell walls. These enzymes assist in nutrient recycling and potential industrial applications (Kumar & Kannan, 2011) , (Tseng et al., 2002) . Does B. firmus have medical or probiotic uses? Yes. It stimulates the immune system, especially IgA and IgG production, and has shown adjuvant potential in mucosal immunization studies (Prokešová et al., 2008). 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    < Crop Kits Neem Plus Neem Plus is a water-soluble neem and karanja-based bio-formulation targeting over 400 crop pests. Product Enquiry Download Brochure Biodegradable and Residue-Free The pesticide is environmentally safe, fully biodegradable, and leaves no harmful residues. Safe and Compatible Harmless to beneficial insects and compatible with other pesticides and fungicides in pH ranges from 5.5 to 6.5. Resistance Prevention The limonoid spectrum in Neem Plus hinders the development of resistance in pests. Multi-Action Insect Control Acts as a repellent, antiovipositor, and insect growth regulator, disrupting key stages of the pest life cycle. Benefits Content coming soon! Composition Dosage & Application Additional Info Dosage & Application For Bollworm, White fly: Use 2.5–5 ml of formulation Dilute in 500–1000 ml of water Waiting period: 5 days before harvest For Thrips, Stem Borer, Leaf folder, Brown Plant Hopper: Use 1.5–2.5 ml of formulation Dilute in 500 ml of water Waiting period: 5 days before harvest HOW TO USE? Neem Protect can be mixed with water and used in spray pumps. Normally oil and water don’t mix, however NEEM PLUS comes with a ready-to-use formulation which you can directly mix with water and start using on your plants. Spray the mixed solution on all the leaves, especially the undersides. When spraying for the first time, drench the soil around the roots as well as it is even good for your soil. Instructions to Open Open the bottle outdoors with care. Do not shake the bottle before opening. The bottle has a double seal system — an external black cap and a white inner plug with a nozzle in the centre. After opening the black outer cap, the inner plug has to be pierced in the middle using any pointed tool. The nozzle should give way, with a small hole, through which the liquid fertiliser can pour out. Additional Info Storage Requirements Store below 40°C in a cool, dry, well-ventilated place. Keep away from sunlight, children, and animals. Do not store in metallic containers. Keep tightly closed when not in use. Handling Precautions Use standard hygiene and safety practices for agricultural products. Related Products Aminomax SP Annomax BioProtek Biocupe Seed Protek Silicomax Dates Pro BloomX More Products Resources Read all

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