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Looking for Biocupe wheat crop solution? A plant health product that improves soil activity, supports disease resistance, and enhances yield quality. Get product enquiry. < Crop Kits Biocupe Biocupe is a spore-based biofungicide containing Chaetomium cupreum for foliar and soil use against fungal diseases. Product Enquiry Download Brochure Dual Mode of Action Combats pathogens through substrate competition and enzymatic degradation of host cell walls, boosting natural plant defenses. Broad-Spectrum Disease Suppression Effective against a wide range of pathogens including rust, early scourage, late curse, leaf spot, stem decay, and tuber decay. IPM Compatibility Functions as a valuable component of Integrated Pest Management programs, helping reduce chemical inputs and creating a safer growing environment. Improves Plant Health and Yield Enhances overall plant wellbeing, resulting in higher productivity and profitability. Benefits Content coming soon! Composition Dosage & Application Additional Info Dosage & Application Foliar application Dose: 5g/L water 1 Acre dose: 1kg 1 Ha dose: 2.5kg Additional Info Mode of Action Substrate Competition for space and Nutrients: Chaetomium cupreum colonizes maximum space and absorbs maximum nutrients available at the target site and thereby controls the pathogens by starving them for food and competing for space — Domino effect. Enzyme production: Chaetomium cupreum produces certain enzymes which dissolve the host cell wall and penetrate and inactivate the host defense mechanism. Storage Requirements Store below 40°C in a cool, dry, well-ventilated place. Keep away from sunlight, children, and animals. Do not store in metallic containers. Keep tightly closed when not in use. Handling Precautions Use standard hygiene and safety practices for agricultural products. Related Products Aminomax SP Annomax BioProtek Neem Plus Seed Protek Silicomax Dates Pro BloomX More Products Resources Read all

Serendipita indica (formerly Piriformospora indica) is a highly effective endophytic fungus recognized for significantly boosting plant growth, resilience, and productivity through beneficial root colonization. Known for its wide range of beneficial effects, Serendipita indica is extensively utilized in agriculture, horticulture, forestry, and medicinal plant cultivation to optimize plant health and performance. < Microbial Species Serendipita indica Serendipita indica (formerly Piriformospora indica) is a highly effective endophytic fungus recognized for significantly boosting plant growth, resilience, and productivity through beneficial root colonization. Known for its wide range of beneficial effects, Serendipita indica is extensively utilized in agriculture, horticulture, forestry, and medicinal plant cultivation to optimize plant health and performance. Strength 245-10000 spores/g Product Enquiry Buy this species Download Brochure Benefits Increased Plant Growth Stimulates biomass accumulation and overall plant vigor by enhancing nutrient efficiency and activating growth-promoting pathways. Enhanced Disease Resistance Strengthens plant immunity by inducing systemic resistance, activating defense genes, and protecting against fungal and bacterial pathogens. Optimized Nutrient Absorption Improves nitrogen, phosphorus, and iron uptake, ensuring better nutrient availability and utilization, even in nutrient-deficient soils. Hormonal Regulation Modulates phytohormones like auxins and gibberellins, promoting root elongation, lateral root formation, and improved stress adaptation for healthier plant development. Dosage & Application Additional Info Scientific References Mode of Action Sustainability Advantage FAQ Scientific References Saleem et al., 2022, "Serendipita indica—A Review from Agricultural Point of View," Plants, MDPI. Singhal et al., 2017, "Piriformospora indica (Serendipita indica): The Novel Symbiont," Springer International. Wu et al., 2018, "Endophytic fungus Serendipita indica increased nutrition absorption and biomass accumulation in Cunninghamia lanceolata seedlings under low phosphate," Acta Ecologica Sinica. Wu et al., 2017, "Changes in gas exchange, root growth, and biomass accumulation of Platycladus orientalis seedlings colonized by Serendipita indica," Journal of Forestry Research. Mode of Action Serendipita indica initiates a symbiotic relationship by colonizing plant roots intracellularly and intercellularly without harming the plant tissues. Upon colonization, the fungus releases beneficial signaling compounds and enzymes that enhance plant physiological and metabolic processes. This symbiotic relationship leads to a multitude of beneficial effects, including: Enhanced Nutrient Uptake: Serendipita indica activates specific nutrient transporters in the plant roots, significantly improving the absorption of essential nutrients such as phosphorus, nitrogen, and trace elements from the soil. Hormonal Modulation: It influences the synthesis and regulation of essential plant hormones such as auxins, cytokinins, gibberellins, and ethylene, promoting root growth, plant development, flowering, and fruit setting. Antioxidant and Stress Response Activation: Serendipita indica boosts the plant's natural antioxidant mechanisms, increasing the activity of antioxidant enzymes like superoxide dismutase (SOD), catalase (CAT), and peroxidase (POD). This leads to improved resilience against oxidative stress induced by environmental challenges such as drought, salinity, heat, and heavy metal toxicity. Enhanced Photosynthesis Efficiency: By optimizing nutrient availability and hormonal balance, Serendipita indica significantly improves photosynthetic efficiency and chlorophyll content in plants, resulting in better energy capture and growth. Systemic Resistance and Disease Protection: The fungus triggers systemic acquired resistance (SAR) and induced systemic resistance (ISR) pathways in host plants. This activates the plant’s natural defense mechanisms, offering protection against various soil-borne and airborne pathogens, reducing disease incidence and severity. Root System Expansion: Serendipita indica significantly enhances root architecture, promoting denser and more extensive root systems. Improved root structure aids in better water retention and soil stability, resulting in stronger, healthier plants. Additional Info Applications and Recommended Crops: Agricultural Crops: Wheat, maize, rice, soybean, tomatoes, cucumbers, and peppers. Horticultural Crops: Grapes, citrus fruits, berries, apples, and stone fruits. Medicinal Herbs: Basil, turmeric, ginger, ashwagandha. Ornamentals and Forestry: Ornamental plants, tree seedlings, landscaping projects. Compatibility Compatible with bio pesticides, bio fertilizers and plant growth hormones but not with chemical fertilizers and chemical pesticides Shelf life Stable within 1 year from the date of manufacturing Dosage & Application Recommended Usage: Seed Treatment: Apply 5-10g per kg of seed Root Dip: Mix 10-15g per liter of water, dip roots for 20-30 minutes before transplanting Soil Application: Apply 1-2kg per acre mixed thoroughly into the soil Irrigation: Compatible with drip irrigation at 0.5-1kg per acre Serendipita indica is not classified as an arbuscular mycorrhizal fungus (AMF). Instead, it is an endophytic fungus , belonging to the order Sebacinales. FAQ Can Serendipita indica be used for all crops? Yes, it has a wide host range and is beneficial for numerous agricultural, horticultural, and forestry crops. How quickly does Serendipita indica show results? Initial beneficial effects on root development and nutrient uptake can typically be seen within a few weeks of application. Is Serendipita indica safe for organic farming? Absolutely, Serendipita indica is entirely natural and compliant with organic farming standards. How should Serendipita indica be stored? Store in a cool, dry place away from direct sunlight. Shelf life varies by formulation but is typically 12-24 months under proper storage conditions. Sustainability Advantage Related Products Glomus mosseae Rhizophagus Intraradices More Products Resources Read all

Pacify by Indogulf Bioag supports plant protection with effective crop care for healthier plants, stress handling, and better field management. Contact today. < Plant Protect Pacify Organic, non-lethal rat repellent designed to drive rats from fields, safe for earthworms, grazing animals, and aquatic life. Product Enquiry Download Brochure Benefits Organic and Safe Made from organic derivatives, it doesn’t harm earthworms, hens, grazing, or aquatic animals. Quick Results Visible results within three days, with no rats seen in the field. Dual-Action Repellent Combines consumption-based and smell-based granules to drive rats away effectively. Long-Lasting Effectiveness Offers protection for 30-45 days after application. Composition Amount Wild plant extract 20% Organic matter 70% Acid insoluble silica 10% Total 100.0% Composition Dosage & Application Key Benefits FAQ Additional Info Additional Info Shelf Life & Packaging Storage: Store in a cool, dry place at room temperature Shelf Life: 24 months from the date of manufacture at room temperature Packaging: 1 kg pouch FAQ What is Pacify? Pacify is an organic, non-lethal rat repellent developed for agricultural field use. It is designed to drive rats away from treated areas without functioning as a poison-based rodenticide. How does Pacify work? Pacify works through a dual-action repellent approach. It combines smell-based and consumption-based granules that create an unfavorable environment for rats, helping push them away from burrows, bunds, and treated field areas. Is Pacify a rat poison? No. Pacify is not positioned as a rat poison. It is a non-lethal repellent designed to discourage rat activity and movement in agricultural fields. What is the composition of Pacify? Pacify contains wild plant extract at 20%, organic matter at 70%, and acid insoluble silica at 10%. What is the recommended dosage of Pacify? The recommended dosage is 3 kg per acre or 7.5 kg per hectare . Dosage may be adjusted depending on field conditions, rodent pressure, and specific application requirements. How should Pacify be applied? Apply Pacify near active rat burrows and along field bunds. For burrows, place the product near the burrow opening. For field borders and bunds, apply it in a linear pattern to create a repellent zone. If burrows are not visible, apply the product around the bunds and field perimeter. How quickly can results be seen? Visible results are generally expected within about three days after proper application, with reduced rat visibility and activity in the treated field area. How long does Pacify remain effective? Pacify can remain effective for approximately 30–45 days after application, depending on field conditions, rainfall, irrigation, rodent pressure, and product placement. Is Pacify safe for earthworms and grazing animals? Pacify is designed to be safe for earthworms, hens, grazing animals, and aquatic life when used as recommended. Avoid unnecessary over-application and follow the recommended field-use instructions. Can Pacify be used in organic farming systems? Pacify is made from organic derivatives and is listed as approved for organic agriculture in the supplied product information. Final use should always follow the applicable local organic certification requirements. Can Pacify be used on all crops? Pacify can be used in agricultural fields where rodent pressure is a concern. It is especially useful around bunds, field borders, and burrow-prone zones. Crop-specific use should follow local agronomic guidance and label instructions. When should Pacify be reapplied? Reapply after 30–45 days, or earlier if heavy rainfall, irrigation, soil movement, or high rodent pressure reduces the repellent effect. How should Pacify be stored? Store Pacify in a cool, dry place at room temperature. Keep the pouch sealed when not in use and protect it from moisture and direct sunlight. The product has a shelf life of 24 months from the date of manufacture under recommended storage conditions. Key Benefits Non-Lethal Rodent Repellent for Field Use Pacify is designed to repel rats from agricultural fields without acting as a poison or kill-based rodenticide. It helps drive rats away from treated areas, supporting field protection while avoiding carcass-related hygiene issues. Organic-Based Composition Pacify is formulated with wild plant extract, organic matter, and acid insoluble silica, making it suitable for growers looking for an organic-derived approach to rodent management. Dual-Action Repellent Effect Pacify works through a combination of consumption-based and smell-based repellent action. This helps create an unfavorable environment for rats around burrows, bunds, and field borders. Protects Crops from Rodent Damage By discouraging rat movement and activity in the field, Pacify helps reduce crop damage caused by burrowing, feeding, and field infestation, especially in crops where rodent pressure can affect yield and quality. Field-Friendly and Non-Harmful to Beneficial Life Pacify is designed to be safe for earthworms, grazing animals, hens, and aquatic life when used as recommended, supporting its role in integrated and sustainable crop protection programs. Fast Visible Response Visible field results can typically be observed within around three days after application, depending on infestation level, field conditions, and correct placement around burrows and bunds. Long-Lasting Protection Pacify provides residual repellent protection for approximately 30–45 days after application, helping growers manage rodent pressure over an extended period. Easy Field Application Pacify can be applied directly near active burrows and along field bunds. If burrows are not visible, the material can be applied around bunds and field borders as a preventive repellent barrier. Dosage & Application Dosage 3 kg per acre 7.5 kg per hectare Product quantity required per acre is about 3 kilos 1kg (in 1/2 + out 1/2). In is to be applied at spoon per burrow and out is to be applied around the field on the bunds (linear application). If burrows are not seen in the field, both (in & out) can be mixed and applied on the bunds. The result of the application will be seen by next three days that no rats will be visible and efficiency will last for 30-45 days minimum. Recommended dosage is for guideline purpose only. More effective application rates may exist depending on specific circumstances. Related Products Trichoderma viride Beauveria bassiana Bloom Up Flyban Insecta Repel Larvicare Mealycare Metarhzium Anisopliae More Products Resources Read all

Clostridium butyricum produces butyrate, which nourishes colon cells, enhances gut barrier function, and supports overall gut health and metabolism. < Microbial Species Clostridium butyricum Clostridium butyricum produces butyrate, which nourishes colon cells, enhances gut barrier function, and supports overall gut health and metabolism. Strength 1 x 10⁸ CFU per gram / 1 x 10⁹ CFU per gram / 1 x 10¹⁰ CFU per gram Product Enquiry Buy this species Download Brochure Benefits Support for Digestive Disorders It can aid in the treatment of digestive disorders by restoring microbial balance and improving overall gut function. Short-Chain Fatty Acid Production This probiotic produces butyrate, a short-chain fatty acid that nourishes colon cells and supports gut health. Gut Barrier Function It helps strengthen the gut barrier, reducing intestinal permeability and protecting against pathogens and toxins. Anti-Inflammatory Effects This strain has anti-inflammatory properties that may alleviate symptoms of inflammatory bowel diseases and promote overall gut wellness. Dosage & Application Additional Info Scientific References Mode of Action Sustainability Advantage FAQ Scientific References Content coming soon! Mode of Action Content coming soon! Additional Info Key Features All microbial strains are characterized using 16S rDNA. All products are non-GMO. No animal-derived materials are used. The typical shelf life is 2 years. All strains are screened in-house using high-throughput screening methods. We can customize manufacturing based on the required strength and dosage. High-resilience strains Stable under a wide pH range Stable under a broad temperature range Stable in the presence of bile salts and acids Do not show antibiotic resistance Packaging Material The product is packaged in a multi-layer, ultra-high barrier foil that is heat-sealed and placed inside a cardboard shipper or plastic drum. Shipping Shipping is available worldwide. Probiotic packages are typically transported in insulated Styrofoam shippers with dry ice to avoid exposure to extreme high temperatures during transit. Support Documentation Certificate of Analysis (COA) Specifications Material Safety Data Sheets (MSDS) Stability studies (18 months) Certifications ISO 9001 ISO 22000 HACCP Halal and Kosher Certification (for Lactobacillus strains) FSSAI Dosage & Application Contact us for more details FAQ Content coming soon! Sustainability Advantage Related Products Bifidobacterium animalis Bifidobacterium bifidum Bifidobacterium breve Bifidobacterium infantis Bifidobacterium longum Lactobacillus acidophilus Lactobacillus bulgaricus Lactobacillus casei More Products Resources Read all

< Crop Kits Plant Hopper Plant hoppers feed on rice sap, causing yellowing and wilting. They can also transmit viral diseases, needing integrated pest management. Product Enquiry Download Brochure Benefits Composition Dosage & Application Additional Info Dosage & Application Additional Info Related Products Aminomax SP Annomax BioProtek Biocupe Neem Plus Seed Protek Silicomax Dates Pro More Products Resources Read all

Saccharomyces boulardii is a probiotic yeast that helps maintain gut health and prevents antibiotic-associated diarrhea, promoting digestive balance. < Microbial Species Saccharomyces boulardii Saccharomyces boulardii is a probiotic yeast that helps maintain gut health and prevents antibiotic-associated diarrhea, promoting digestive balance. Strength 1 x 10⁸ CFU per gram / 1 x 10⁹ CFU per gram / 1 x 10¹⁰ CFU per gram Product Enquiry Buy this species Download Brochure Benefits Antimicrobial Properties It inhibits the growth of harmful bacteria and pathogens, contributing to a healthier gut environment and supporting gut health. Support During Antibiotic Use It helps prevent antibiotic-associated diarrhea, promoting gut health during and after antibiotic treatments for optimal recovery. Immune System Enhancement This strain boosts immune function by stimulating the production of antibodies and enhancing the body's defenses against various infections. Digestive Health Support This probiotic yeast helps maintain gut balance, alleviating symptoms of diarrhea and promoting overall digestive comfort and well-being. Dosage & Application Additional Info Scientific References Mode of Action Sustainability Advantage FAQ Scientific References Content coming soon! Mode of Action Content coming soon! Additional Info Key Features All microbial strains are characterized using 16S rDNA. All products are non-GMO. No animal-derived materials are used. The typical shelf life is 2 years. All strains are screened in-house using high-throughput screening methods. We can customize manufacturing based on the required strength and dosage. High-resilience strains Stable under a wide pH range Stable under a broad temperature range Stable in the presence of bile salts and acids Do not show antibiotic resistance Packaging Material The product is packaged in a multi-layer, ultra-high barrier foil that is heat-sealed and placed inside a cardboard shipper or plastic drum. Shipping Shipping is available worldwide. Probiotic packages are typically transported in insulated Styrofoam shippers with dry ice to avoid exposure to extreme high temperatures during transit. Support Documentation Certificate of Analysis (COA) Specifications Material Safety Data Sheets (MSDS) Stability studies (18 months) Certifications ISO 9001 ISO 22000 HACCP Halal and Kosher Certification (for Lactobacillus strains) FSSAI Dosage & Application Contact us for more details FAQ Content coming soon! Sustainability Advantage Related Products Bifidobacterium animalis Bifidobacterium bifidum Bifidobacterium breve Bifidobacterium infantis Bifidobacterium longum Clostridium butyricum Lactobacillus acidophilus Lactobacillus bulgaricus More Products Resources Read all

Bacillus polymyxa improves phosphorus availability by solubilizing phosphate, promotes plant growth through nitrogen fixation and hormone production, and aids bioremediation by breaking down organic pollutants—enhancing soil health for sustainable agriculture. < Microbial Species Bacillus polymyxa Bacillus polymyxa improves phosphorus availability by solubilizing phosphate, promotes plant growth through nitrogen fixation and hormone production, and aids bioremediation by breaking down organic pollutants—enhancing soil health for sustainable agriculture. Strength 1 x 10⁸ CFU per gram / 1 x 10⁹ CFU per gram / 1 x 10¹⁰ CFU per gram Product Enquiry Buy this species Download Brochure Benefits Phosphorus Solubilization: Increases the bioavailability of phosphorus in the soil, promoting better nutrient uptake and plant growth. Root Development: Stimulates robust root formation, leading to stronger plants and improved drought resistance. Soil Health Restoration: Breaks down organic pollutants, contributing to soil bioremediation and improved soil fertility. Sustainable Agriculture: Environmentally safe, enhancing crop productivity without chemical inputs, supporting eco-friendly farming. Dosage & Application Additional Info Scientific References Mode of Action Sustainability Advantage FAQ Scientific References Key Scientific Resources Romeh A.A. & Hendawi M.Y. (2014) “Bioremediation of organophosphorus pesticides by Paenibacillus polymyxa ” — pesticide degradation kinetics in vitro and in soil Characterization of Antagonistic Bacteria Paenibacillus polymyxa ZYPP18 and the Effects on Plant Growth Microbial Phosphorus Solubilization and Its Potential for Use in Sustainable Agriculture Kloepper J.W. et al. (2004) “PGPR seed treatments and soil drenches” — practical guidance on PGPR product placement (method details in ). Mode of Action Bacillus polymyxa (also known as Paenibacillus polymyxa ) exhibits several modes of action, primarily through its production of antimicrobial substances and enzymes. Here's a breakdown of its known mechanisms: Evidence Antimicrobial Compound Production B. polymyxa produces a broad-spectrum antimicrobial compound that is effective against yeasts, fungi, Gram-positive, and Gram-negative bacteria. This compound is different from polymyxins and is highly stable to heat and enzymatic degradation (Rosado & Seldin, 1993). Polymyxin Antibiotic Production It synthesizes polymyxin antibiotics (especially polymyxin B and M), which are effective against Gram-negative bacteria by disrupting bacterial membranes. The biosynthesis is regulated through a membrane-bound multienzyme complex (Vasantha et al., 1980) , (Balakrishnan et al., 1980) . Enzyme Secretion The organism produces various enzymes like proteases, amylases, and dehydrogenases, which contribute to antimicrobial activity and nutrient cycling. Amylase from B. polymyxa degrades starch and dextrins effectively (Robyt & French, 1964) . Regulation of Sporulation and Antibiotic Synthesis Polymyxins regulate B. polymyxa ’s transition from vegetative growth to sporulation, showing that its antibiotics also serve as internal signals (Nefelova et al., 1980) . Biofertilizer and Biocontrol Functions B. polymyxa also acts as a plant growth-promoting rhizobacterium by producing antibiotics like fusaricidin, nitrogen fixation, and phosphate solubilization, suppressing plant pathogens (Padda et al., 2017) . Bacillus polymyxa exerts its effects through antimicrobial compound production, enzyme secretion, antibiotic biosynthesis, and plant growth-promotion, making it a valuable organism in medicine, agriculture, and biotechnology. Additional Info Recommended Crops: Cereals, Millets, Pulses, Oilseeds, Fibre Crops, Sugar Crops, Forage Crops, Plantation crops, Vegetables, Fruits, Spices, Flowers, Medicinal crops, Aromatic Crops, Orchards, and Ornamentals. Compatibility: Compatible with Bio Pesticides, Bio Fertilizers, and Plant growth hormones but not with chemical fertilizers and chemical pesticides. Shelf Life: Stable within 1 year from the date of manufacturing. Packing: We offer tailor-made packaging as per customers' requirements. Dosage & Application Seed Coating/Seed Treatment : 1 kg of seeds will be coated with a slurry mixture of 10 g of Bacillus polymyxa and 10 g of crude sugar in sufficient water. The coated seeds will then be dried in shade and sow or broadcast in the field. Seedling Treatment : Dip the seedlings into the mixture of 100 grams of Bacillus polymyxa and sufficient amount of water. Soil Treatment : Mix 3-5 kg per acre of Bacillus polymyxa with organic manure/organic fertilizers. Incorporate the mixture and spread into the field at the time of planting/sowing. Irrigation : Mix 3 kg per acre of Bacillus polymyxa in a sufficient amount of water and run into the drip lines. FAQ What is Bacillus polymyxa ? Bacillus polymyxa , now more commonly known as Paenibacillus polymyxa , is a soil-dwelling, spore-forming bacterium known for producing antibiotics, promoting plant growth, and acting as a natural biocontrol agent. How does B. polymyxa fight harmful microbes? It produces antimicrobial substances including polymyxins and other heat-stable compounds that can inhibit the growth of bacteria, fungi, and yeasts (Rosado & Seldin, 1993) . What are polymyxins and how do they work? Polymyxins are antibiotics produced by B. polymyxa that target Gram-negative bacteria by disrupting their cell membranes, leading to cell death (Vasantha et al., 1980) . Does B. polymyxa have agricultural benefits? Yes, it is used as a biofertilizer and biocontrol agent. It promotes plant growth by fixing nitrogen, solubilizing phosphate, and producing phytohormones and antifungal compounds like fusaricidin (Padda et al., 2017) . Can B. polymyxa produce enzymes? Yes, it produces enzymes such as amylases and proteases that can break down complex carbohydrates and proteins. These enzymes are useful in industrial applications and soil nutrient cycling (Robyt & French, 1964) . How is antibiotic production linked to sporulation? Polymyxin production and spore formation are interconnected. The presence of polymyxins can regulate when the bacterium forms spores, indicating a dual role in defense and development (Nefelova et al., 1980) . Where is B. polymyxa commonly found? It is found in diverse environments including soil, plant roots, and marine sediments. Its ability to adapt and colonize various habitats contributes to its usefulness in ecological and agricultural applications. Sustainability Advantage Related Products Saccharomyces cerevisiae Aspergillus awamori Bacillus firmus Bacillus megaterium: Phosphate solubilizing bacteria for agriculture Pseudomonas putida: Beneficial Rhizobacteria for Plant Growth and Phosphorus Availability Pseudomonas striata Thiobacillus novellus Thiobacillus thiooxidans More Products Resources Read all

Revive Bio soil fertilizer by Indogulf BioAg: Organic, eco-friendly, and certified for robust plant health. Trusted globally for enhanced crop yields. < Soil Fertilizers Revive Bio Bio-fertilizer with nitrogen-fixing bacteria. Available in powder form, reduces the need for fertilizers and provides balanced nutrition for superior crop production. Product Enquiry Download Brochure Benefits Secretes Plant Growth Hormones and Regulators Stimulates plant growth and development through the secretion of hormones, promoting vigorous and resilient plants. Decreases or Removes the Need for Chemical Fertilizer Reduces reliance on chemical fertilizers by providing essential nutrients in organic form, supporting sustainable farming practices. Provides Soil Aeration and Increases Water Holding Capacity Improves soil structure, enhancing aeration and water retention, crucial for optimal plant growth. Prevents Plant Growth with Biopesticidal Effect Naturally inhibits plant pests, promoting healthier plant growth without relying on chemical pesticides. Dosage & Application Kit Contents Composition Key Benefits FAQ Additional Info Dosage & Application Powder Dosage Soil Application: Mix ½ kg of Revive powder with 10 kg of sand or vermiculite, and spread uniformly over 1 acre of land. Water after planting. Seed Inoculation: Use 250 grams of Revive powder for 10 to 15 kg of seeds. Make a slurry by adding adequate water and the required quantity of Revive powder to the seeds. Leave the slurry overnight, then dry the seeds in the shade before sowing. Seedling Inoculation: Mix 2 kg of Revive powder with adequate water. Dip the roots of seedlings required for one acre in the mixture for 8 to 12 hours, then transplant the seedlings. Foliar Application: Mix 20 grams of Revive powder with 2 liters of water and spray on the crops, targeting leaves and roots. Spray volume depends on crop canopy. Liquid Dosage Soil Application: Mix 2.5 liters of Revive (bio) in 300 liters of water and spray over 12 acres. Repeat after 15 days. Seed Inoculation: Use 250 ml of Revive (bio) for 10 to 15 kg of seeds. Make a slurry by adding adequate water and the required quantity of Revive (bio). Apply the slurry uniformly to the seeds, then dry them in the shade before sowing. Seedling Inoculation: Mix 2 liters of Revive (bio) with water. Dip the roots of seedlings required for one acre in the mixture, then transplant the seedlings. Foliar Application: Mix 20 ml of Revive (bio) with 2 liters of water for foliar spray. Spray volume depends on crop canopy. Additional Info Mode of Action Provides atmospheric nitrogen fixation to meet the nitrogen needs of plants. Transforms phosphorus and potassium salts in the soil into forms that plants can absorb. Secretes plant growth hormones and regulators. Breaks down harmful compounds in the plant cultivation medium. Suppresses microorganisms that may inhibit plant growth with biopesticidal effects. Enhances the natural, chemical, and biological structure of the soil by increasing its organic content. Improves soil aeration and increases its water-holding capacity. Reduces or eliminates the need for chemical fertilizers. Recommended Crops Cereals, Millets, Pulses, Oilseeds, Fibre Crops, Sugar Crops, Forage Crops, Plantation Crops, Vegetables, Fruits, Spices, Flowers, Medicinal Crops, Aromatic Crops, Orchards, and Ornamentals Shelf Life & Packaging: Storage: Store in a cool, dry place at room temperature Shelf Life: 24 months from the date of manufacture at room temperature Packaging: 1 kg / 20 litre FAQ Content coming soon! Kit Contents Content coming soon! Composition Content coming soon! Key Benefits Content coming soon! Related Products Bio-Manna Bio-Manure Fermogreen Neem Powder More Products Resources Read all

Paenibacillus azotofixans: Utilized in agricultural practices to promote plant growth by fixing atmospheric nitrogen, thus improving soil fertility, especially in various crop fields. < Microbial Species Paenibacillus azotofixans Paenibacillus azotofixans: Utilized in agricultural practices to promote plant growth by fixing atmospheric nitrogen, thus improving soil fertility, especially in various crop fields. Strength 1 x 10⁸ CFU per gram / 1 x 10⁹ CFU per gram / 1 x 10¹⁰ CFU per gram Product Enquiry Buy this species Download Brochure Benefits Nitrogen Fixation Paenibacillus azotofixans fixes atmospheric nitrogen into ammonia, which enhances nitrogen availability for plants, supporting their growth and development. Plant Growth Promotion Paenibacillus azotofixans produces phytohormones like auxins and cytokinins, which stimulate root growth and increase the efficiency of nutrient and water uptake. Disease Suppression It exhibits antagonistic activity against various plant pathogens, helping to suppress diseases and enhance plant health through competition and antibiotic production. Phosphate Solubilization It solubilizes phosphate in the soil, making it more accessible to plants, which improves their phosphorus uptake and overall nutrient status. Dosage & Application Additional Info Scientific References Mode of Action Sustainability Advantage FAQ Scientific References Molecular Biology and Genetics Genome-Scale Studies: Comprehensive transcriptome analysis of nitrogen fixation in Paenibacillus species has identified over 9,000 differentially expressed genes involved in nitrogen metabolism, energy production, and stress response. These studies provide detailed insights into the molecular mechanisms underlying nitrogen fixation efficiency. biomedcentral Phylogenetic Analysis: Molecular phylogenetic studies based on nifH gene sequences demonstrate that Paenibacillus azotofixans nitrogen-fixing genes cluster with cyanobacterial and archaeal nitrogenases, suggesting ancient evolutionary origins and potential for high activity. journals.asm Regulatory Mechanisms: Advanced molecular studies have elucidated complex regulatory networks involving GlnR, AdeR, and other transcriptional regulators that control nitrogen fixation in response to environmental conditions. microbialcellfactories.biomedcentral+1 Field Performance and Agricultural Applications Multi-Location Trials: Extensive field trials across different climatic zones and soil types consistently demonstrate the effectiveness of Paenibacillus azotofixans for enhancing crop productivity. These studies provide robust evidence for the bacterium's agricultural value under diverse conditions. pmc.ncbi.nlm.nih+1 Long-Term Sustainability: Research demonstrates that repeated application of Paenibacillus azotofixans maintains soil health and fertility without negative environmental impacts. Long-term studies show sustained benefits over multiple growing seasons. pmc.ncbi.nlm.nih Economic Analysis: Cost-benefit analyses demonstrate positive returns on investment from Paenibacillus azotofixans applications, with reduced fertilizer costs offsetting inoculation expenses while providing additional yield benefits. cropj Mode of Action Nitrogen Fixation Biochemistry Paenibacillus azotofixans employs a highly regulated nitrogenase system consisting of multiple enzyme complexes that work together to reduce atmospheric nitrogen: journals.asm+1 Oxygen Sensitivity Management: As an obligate anaerobe process, nitrogen fixation by nitrogenase requires oxygen-free conditions. Paenibacillus azotofixans creates localized anaerobic microenvironments through rapid oxygen consumption and biofilm formation. biomedcentral Energy Requirements: The nitrogen fixation process requires substantial ATP input (16 molecules of ATP per molecule of N₂ fixed). Paenibacillus azotofixans meets this energy demand through efficient carbohydrate metabolism and optimized electron transport chains. biomedcentral Metal Cofactor Utilization: The nitrogenase enzyme complex requires molybdenum, iron, and sulfur cofactors. Paenibacillus azotofixans possesses specialized transport systems for acquiring and concentrating these essential metals. biomedcentral Metabolic Integration and Regulation Ammonium Tolerance Mechanisms: Recent research has revealed that certain Paenibacillus species can overcome ammonium inhibition of nitrogen fixation through alanine dehydrogenase (ADH) activity. This mechanism allows continued nitrogen fixation even in soils with moderate nitrogen availability. microbialcellfactories.biomedcentral Carbon-Nitrogen Balance: The bacterium maintains optimal carbon-nitrogen ratios through sophisticated regulatory networks that coordinate nitrogen fixation with carbon metabolism. This integration ensures efficient resource utilization and sustained bacterial activity. journals.asm Stress Response Systems: Paenibacillus azotofixans possesses multiple stress response mechanisms that maintain nitrogen fixation activity under challenging environmental conditions including drought, temperature extremes, and pH variations. microbialcellfactories.biomedcentral Applications in Biofertilizers and Soil Health Management Commercial Biofertilizer Formulations Paenibacillus azotofixans serves as a key component in advanced biofertilizer formulations designed for various agricultural applications: indogulfbioag+1 Multi-Strain Consortiums: Commercial products often combine Paenibacillus azotofixans with complementary bacteria such as phosphorus-solubilizing bacteria and biocontrol agents to provide comprehensive plant nutrition and protection. indogulfbioag Crop-Specific Formulations: Different application methods and strain combinations are optimized for specific crops and growing conditions. Soybean formulations may emphasize nitrogen fixation, while vegetable applications focus on rapid establishment and growth promotion. cropj Delivery Systems: Paenibacillus azotofixans can be formulated for seed treatment, soil application, or irrigation system delivery, providing flexibility for different farming operations. indogulfbioag Integration with Sustainable Farming Practices Organic Agriculture: As a naturally occurring, non-GMO bacterium, Paenibacillus azotofixans is approved for organic farming systems and supports organic certification requirements. indogulfbioag Precision Agriculture: The bacterium can be integrated into precision farming systems where GPS-guided application ensures optimal placement and dosing based on field-specific soil conditions and crop requirements. Conservation Agriculture: Paenibacillus azotofixans supports no-till and reduced-tillage farming systems by maintaining soil biological activity and nitrogen availability without mechanical soil disturbance. Paenibacillus Species Diversity and Agricultural Significance The Broader Paenibacillus Genus The Paenibacillus species represent one of the most diverse bacterial genera in soil ecosystems, with over 211 described species exhibiting remarkable genetic and phenotypic diversity. This diversity reflects extensive horizontal gene transfer and adaptive evolution that has enabled Paenibacillus species to colonize diverse environmental niches. pmc.ncbi.nlm.nih+1 Genomic Diversity: Comparative genomic analyses reveal that Paenibacillus species possess highly variable genome sizes ranging from 3.9 to 10.4 megabases, with extensive variation in gene content even within species. This genomic plasticity underlies the genus's exceptional environmental adaptability. nature Metabolic Versatility: Paenibacillus species demonstrate remarkable metabolic diversity, with different species specialized for various functions including nitrogen fixation, phosphate solubilization, biocontrol, and organic matter decomposition. This metabolic diversity makes them valuable for diverse agricultural applications. nature Nitrogen-Fixing Paenibacillus Species Multiple Paenibacillus species possess nitrogen-fixing capabilities, each adapted to specific environmental conditions and plant associations: frontiersin+1 Paenibacillus polymyxa: Perhaps the most extensively studied species, demonstrating nitrogen fixation, biocontrol activity, and plant growth promotion across numerous crop species. pmc.ncbi.nlm.nih+1 Paenibacillus borealis: Isolated from forest humus, this species contributes to nitrogen cycling in forest ecosystems and demonstrates potential for forestry applications. microbiologyresearch Paenibacillus graminis: Associated with grass rhizospheres, this species enhances nitrogen availability in forage and turf systems. frontiersin Additional Info Incomplete Section Finalization Paenibacillus azotofixans is recognized for its agricultural significance as a potent nitrogen fixer and plant growth promoter. Modern molecular biology and field-scale studies have validated its benefits for crop nutrition, environmental sustainability, and cost-effectiveness. The bacterium’s versatility and resilience are supported by its diverse regulatory, metabolic, and stress response mechanisms, which make it compatible across a wide range of soil conditions and crop systems. Laboratory Contaminant Significance Paenibacillus species are widely distributed in natural and built environments, including soil, water, and air. Their ability to form spores and survive harsh conditions means they are frequent laboratory contaminants. In clinical and research laboratories, Paenibacillus can be isolated from surfaces, air, gloves, and sample materials—often as part of sterility testing. Several species, including Paenibacillus contaminans, have been specifically described as contaminants during laboratory plate handling. This is particularly relevant in low-biomass environments, as modern sequencing or culture approaches can easily detect spores or cells introduced during sample processing or from ambient air. The high occurrence of Paenibacillus as a contaminant can result in false-positive results, especially in blood cultures, sterile fluids, or low-biomass samples. Proper sample collection, rigorous sterilization, and careful interpretation of culture results are imperative. Contaminants are often identified retrospectively by phylogenetic and phenotypic analysis and may comprise the majority of positive cultures unless clear clinical evidence of infection is present. pmc.ncbi.nlm.nih+3 Human Pathogenicity Paenibacillus species are generally regarded as environmental and plant-associated bacteria. However, accumulating evidence shows that a subset can act as opportunistic pathogens in humans—particularly in immunocompromised individuals, neonates, or following traumatic injuries. Human infections are rare but increasingly described in clinical case reports and systematic reviews. Several species implicated in human disease include P. alvei, P. thiaminolyticus, P. lautus, P. provencensis, and others. Infections range from wound infections, abscesses, ocular infections, sepsis, meningitis, and, rarely, endocarditis. Pathogenicity is driven by several factors: Spore formation and environmental resilience: Spores remain viable on skin surfaces and within hospital environments, making transmission and infection possible under specific conditions. d-nb+1 Virulence factors: Some Paenibacillus possess genes for thiol-activated cytolysins, proteases, biofilm formation, and antimicrobial compound production. journals.plos+3 Antibiotic resistance: Many isolates demonstrate resistance to multiple antibiotics, particularly penicillins, clindamycin, sulfonamides, and sometimes vancomycin, calling for careful susceptibility testing. pure.psu+4 Clinical Management Recommendations Management of Paenibacillus infections hinges on accurate diagnosis and effective antimicrobial therapy. As precaution, clinicians should: Differentiate true infection from contamination: Always correlate positive cultures with clinical signs (fever, leukocytosis, infection at the site), especially when Paenibacillus is isolated from blood, sterile fluids, or deep wounds. pmc.ncbi.nlm.nih+2 Empiric and directed antibiotic therapy: Initial therapy is empiric, but due to variable resistance patterns, therapy should be adjusted based on susceptibility testing. Effective options typically include cefotaxime, ceftriaxone, gentamicin, amikacin, rifampicin, metronidazole, and levofloxacin, while resistance to penicillins, clindamycin, and vancomycin can occur. Trimethoprim-sulfamethoxazole may be used for P. urinalis. droracle+6 Remove or drain infection sources: Surgical removal of infected tissues, foreign bodies, or abscess drainage may be necessary in localized infections. Monitor for complications: Especially in infants, Paenibacillus can cause severe complications like meningitis and hydrocephalus, requiring close monitoring and sometimes neurosurgical intervention. thelancet+2 Follow-up and continuity of care: Persistent infections require long-term medical follow-up and sometimes prolonged antibiotic administration. pmc.ncbi.nlm.nih+1 Current Knowledge of Human Infections Systematic reviews and case series demonstrate that although Paenibacillus species are uncommon human pathogens, the number of species associated with clinical infections is growing. Infection presentations differ notably between adults and infants: Adults: Infections are sporadic, caused by a wide array of species, often present as wound infections, abscesses, or localized sepsis. Central nervous system involvement is rare, and most cases resolve with treatment. pubmed.ncbi.nlm.nih+2 Infants: Neonatal infections are far more severe, especially with P. thiaminolyticus, and often present as sepsis or meningitis with a high risk of cerebral destruction and hydrocephalus. Mortality rates are notable, and survivors often need surgical intervention for neurological sequelae. pmc.ncbi.nlm.nih+3 The overall frequency of infection remains low relative to the ubiquity of the genus, indicating that most isolates are contaminants, but vigilance is still warranted for at-risk populations. Recommended Crops: Cereals, Millets, Pulses, Oilseeds, Fibre Crops, Sugar Crops, Forage Crops, Plantation crops, Vegetables, Fruits, Spices, Flowers, Medicinal crops, Aromatic Crops, Orchards, and Ornamentals. Compatibility: Compatible with Bio Pesticides, Bio Fertilizers, and Plant growth hormones but not with chemical fertilizers and chemical pesticides. Shelf Life: Stable within 1 year from the date of manufacturing. Packing: We offer tailor-made packaging as per customers' requirements. Dosage & Application Seed Coating/Seed Treatment: Coat 1 kg of seeds with a slurry mixture of 10 g of Paenibacillus Azotofixans and 10 g of crude sugar in sufficient water. Dry the coated seeds in shade before sowing or broadcasting in the field. Seedling Treatment: Dip seedlings into a mixture of 100 grams of Paenibacillus Azotofixans with sufficient water. Soil Treatment: Mix 3-5 kg per acre of Paenibacillus Azotofixans with organic manure or fertilizers. Incorporate into the soil during planting or sowing. Irrigation: Mix 3 kg per acre of Paenibacillus Azotofixans in water and apply through drip lines. FAQ What is the significance of Paenibacillus as a potential laboratory contaminant? Answer: Paenibacillus species are among the most frequently isolated laboratory contaminants, especially in low-biomass and sterile sample environments. Their spores persist in air, on surfaces, and even on personal protective equipment, leading to inadvertent contamination of cultures and clinical specimens. Laboratory contaminants can cause diagnostic confusion, particularly when isolated from blood cultures or sterile sites, given the genus’s environmental prevalence. Recognizing Paenibacillus as a contaminant is vital to prevent misdiagnosis, unnecessary antimicrobial therapy, and misleading research conclusions. Rigorous sample handling and critical assessment of laboratory results are essential in distinguishing contamination from true infection. sciencedirect+4 Can Paenibacillus species exhibit pathogenicity in humans? Answer: Although primarily environmental and plant-associated, certain Paenibacillus species can exhibit pathogenicity in humans, particularly in vulnerable populations such as neonates, immunocompromised individuals, or following trauma. Documented infections include sepsis, wound infection, abscesses, meningitis, endocarditis, ocular infections, and rare systemic disease. Species like P. alvei, P. thiaminolyticus, and P. lautus are increasingly identified as clinical pathogens. In neonates, P. thiaminolyticus is notably associated with severe CNS infections. Virulence factors, antibiotic resistance, and spore persistence contribute to pathogenic potential, although true infections remain rare compared to environmental contamination. wwwnc.cdc+9 What are the recommended clinical approaches for managing Paenibacillus infections? Answer: Management is guided by accurate diagnosis and susceptibility-directed antimicrobial therapy. Clinicians should distinguish true infection from laboratory contamination, correlate culture results with clinical findings, and employ targeted treatment. Empiric therapy can include cefotaxime, ceftriaxone, gentamicin, amikacin, levofloxacin, and rifampicin, but resistance to penicillin, clindamycin, vancomycin, and sulfonamides is not uncommon. Susceptibility testing is imperative prior to finalizing antibiotic choice. Additional interventions such as surgical drainage of infected tissues may be necessary. Neonatal and CNS infections require close multidisciplinary management. Long-term monitoring is advised due to the potential for persistent or recurrent infection and post-infectious complications. pmc.ncbi.nlm.nih+7 What is currently known about human infections caused by Paenibacillus species? Answer: Human Paenibacillus infections, while uncommon, are increasingly recognized in pediatric and adult populations. Infections in adults are sporadic and generally mild, presenting as localized wound infection, abscesses, or sepsis, and most affected individuals recover without severe sequelae. Neonatal infections, especially those due to P. thiaminolyticus, are severe and often complicated by brain injury, hydrocephalus, and require surgical intervention, with notable associated mortality. The rise in documented cases reflects improved detection, growing awareness, and advances in microbiological diagnostics. Nonetheless, the majority of clinical isolates are contaminants rather than true pathogens, highlighting the importance of careful clinical interpretation and management. Ongoing research is elucidating new species, virulence mechanisms, and optimized treatment protocols. sciencedirect+9 Sustainability Advantage Related Products Acetobacter xylinum Azospirillum brasilense Azospirillum lipoferum Azospirillum spp. Azotobacter vinelandii Beijerinckia indica Bradyrhizobium elkanii Bradyrhizobium japonicum More Products Resources Read all

Neem extracts from Azadirachta indica contain Azadirachtin, toxic to pests, acting as antifeedant, repellent, and sterilizer. Organic gardeners use it for pest control. < Microbial Species Neem Extracts from Azadirachta Indica Tree Neem extracts from Azadirachta indica contain Azadirachtin, toxic to pests, acting as antifeedant, repellent, and sterilizer. Organic gardeners use it for pest control. Strength 2500 - 50000ppm Product Enquiry Buy this species Download Brochure Benefits Environmental Compatibility Neem extracts degrade rapidly, leaving no harmful residues and posing minimal risk to non-target species and ecosystems. Sterilizing Effect on Pests Neem extracts induce sterility in insect pests, reducing their reproductive capabilities and population growth. Insect Repellent Properties Neem extracts, containing Azadirachtin, act as antifeedants and repellents against insect pests, disrupting feeding and reducing infestation. Antifungal Activity Azadirachtin in neem extracts exhibits fungicidal properties, effectively controlling fungal diseases like powdery mildew and leaf rust. Dosage & Application Additional Info Scientific References Mode of Action Sustainability Advantage FAQ Scientific References Content coming soon! Mode of Action Content coming soon! Additional Info Target pests: Aphids, whiteflies, spider mites, powdery mildew, leaf rust Recommended Crops: Cereals, millets, pulses, oilseeds, fibre crops, sugar crops, forage crops, plantation crops, vegetables, fruits, spices, flowers, medicinal crops, aromatic crops, orchards, and ornamentals Compatibility: Compatible with Bio Pesticides, Bio Fertilizers, and Plant growth hormones but not with chemical fertilizers and chemical pesticides. Shelf Life: Stable within 1 year from the date of manufacturing. Packing: We offer tailor-made packaging as per customers' requirements. Dosage & Application Contact us for more details FAQ Content coming soon! Sustainability Advantage Related Products More Products Resources Read all