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- Liv Care Manufacturer and Exporter | Direct fed Microbials for Aquaculture | Indogulf BioAg
< Animal Health Livcare Liv Care is a specialty formulation for treatment of fish & shrimps to improve their liver functioning and aiding in digestion. Product Enquiry Benefits Boosts Immunity and Disease Resistance Strengthens the immune system and improves resistance to common diseases in fish, prawns, and shrimp. Improves Appetite, Digestion, and Nutrient Assimilation Enhances feeding behavior, supports efficient digestion, and promotes better nutrient absorption, leading to healthy weight gain. Protects Liver and Enhances Growth Performance Prevents fatty liver infiltration, reduces feed wastage by increasing appetite, and supports sustained growth and healthy production. Supports Metabolism and Nutritional Efficiency Activates key enzymes involved in metabolic processes, ensuring optimal utilization of a proper nutritional diet. Component Amount per 30 mL Thiamine HCl 5 mg Ferrous Chloride 80 mg Nicotinic Acid 20 mg Nicotinamide 45 mg Ferrous Gluconate 200 mg Riboflavin 5 mg Calcium Lactate 300 mg Silymarin 100 mg Liver Fraction (II) (from 3.75g fresh liver) 150 mg Aqueous Base 30 mg Composition Distinction FAQ Additional Info FAQ Content coming soon! Dosage & Application Content coming soon! Additional Info Content coming soon! Related Products Piscicare Aquatract Aqua Energy Aqua Pro Aquamin Probio Aqua More Products Resources Read all
- Aspergillus Oryzae Manufacturer & Exporter | Bio Compost Degrading | Microbial Species | Indogulf BioA
Aspergillus oryzae is a filamentous fungus widely utilized in industrial and agricultural applications due to its enzymatic versatility. It plays a crucial role in food and beverage fermentation by producing amylases, cellulases, and proteases, which catalyze the breakdown of complex carbohydrates and proteins. In agriculture, A. oryzae is integral to composting processes, where its enzymatic activity accelerates the decomposition of organic matter, enhancing nutrient cycling and improving soil fertility. The ability of A. oryzae to convert agricultural waste into nutrient-rich compost makes it a critical component of sustainable farming practices and organic waste management, bridging industrial biotechnology and eco-friendly agricultural and environmental solutions. < Microbial Species Aspergillus oryzae Aspergillus oryzae is a filamentous fungus widely utilized in industrial and agricultural applications due to its enzymatic versatility. It plays a crucial role in food and beverage fermentation by producing amylases, cellulases, and proteases, which catalyze the breakdown of complex carbohydrates and proteins. In agriculture, A. oryzae is integral to composting processes, where its enzymatic activity accelerates the decomposition of organic matter, enhancing nutrient cycling and improving soil fertility. The ability of A. oryzae to convert agricultural waste into nutrient-rich compost makes it a critical component of sustainable farming practices and organic waste management, bridging industrial biotechnology and eco-friendly agricultural and environmental solutions. Strength 1 x 10⁸ CFU per gram / 1 x 10⁹ CFU per gram / 1 x 10¹⁰ CFU per gram Product Enquiry Buy this species Download Brochure Benefits Breaks down complex carbohydrates It produces enzymes that break down complex carbohydrates into simpler sugars, aiding in digestion and nutrient availability. Enhances enzyme activity in compost Aspergillus oryzae's enzymes can also enhance the breakdown of organic matter in composting, improving compost quality. Improves fermentation efficiency Aspergillus oryzae is known for its ability to enhance the fermentation process, particularly in food and beverage production. Increases nutrient availability By breaking down complex compounds, Aspergillus oryzae increases the availability of essential nutrients for plants and microorganisms. Dosage & Application Additional Info Scientific References Mode of Action Sustainability Advantage FAQ Scientific References Sun et al., 2024. "Aspergillus oryzae as a Cell Factory: Research and Applications in Industrial Production," Journal of Fungi. Daba et al., 2021. "The ancient koji mold (Aspergillus oryzae) as a modern biotechnological tool," Bioresources and Bioprocessing. Mode of Action Aspergillus oryzae demonstrates a potent secretory system, efficiently secreting hydrolytic enzymes that catalyze the breakdown of complex substrates such as proteins, starches, lipids, cellulose, and pectins. The enzymes produced by Aspergillus oryzae are highly stable and active under various environmental conditions, making them highly effective for industrial-scale applications. Industrial Enzymes Produced by Aspergillus oryzae: Proteases: Crucial in food processing, pharmaceutical, and detergent industries, proteases from Aspergillus oryzae aid in protein hydrolysis, improving product texture and nutritional value. Amylases (α-amylase, glucoamylase): Widely used in food processing for starch hydrolysis and alcohol fermentation, enhancing efficiency and product quality. Lipases: Effective in enhancing flavor and aroma in dairy products, widely used in detergents and cosmetics. Cellulases and Pectinases: Essential for textile processing, fruit juice clarification, and biomass conversion into fermentable sugars. Additional Info Food Industry: Production of fermented foods, beverages, and enhanced texture and flavor of dairy products. Animal Feed: Improves nutrient absorption, digestion, and overall health in poultry, livestock, and aquaculture. Pharmaceuticals: Production of active pharmaceutical ingredients (APIs), vitamins, and secondary metabolites. Detergent and Textile: Enhances cleaning power in detergents and improves textile processing efficiency. Available Forms: Water soluble powder, liquid suspensions Concentration: Optimized for industrial-scale enzyme production. Packaging: Customizable packaging sizes suitable for small-scale to bulk industrial applications Dosage & Application Industrial Applications: Solid-state Fermentation: 1-2 kg per ton of substrate Submerged Fermentation: 100-200 grams per cubic meter of fermentation broth Animal Feed: Poultry and Livestock: 0.1-0.5% inclusion rate in feed formulations Aquaculture: 0.2-0.4% inclusion rate in feed formulations Agricultural Applications: Composting: 500 grams - 1 kg per cubic meter of compost Soil Application: Mix 1-2 kg per hectare directly into the soil before planting Organic Waste Management: 1-2 kg per ton of organic waste material FAQ Is Aspergillus oryzae safe for food production? Yes, it is recognized as safe by the FDA (GRAS status) and extensively utilized globally in various food processing applications without adverse health effects. Get detailled information about What Is Aspergillus Oryzae Used for in Food ? How does Aspergillus oryzae improve soil fertility? Aspergillus oryzae accelerates organic matter decomposition through its potent enzymatic activity, enhancing nutrient cycling, increasing soil nutrient availability, and promoting overall soil health. Check this how does Aspergillus oryzae improve soil fertility ? What makes Aspergillus oryzae enzymes effective under industrial conditions? Enzymes produced by Aspergillus oryzae demonstrate remarkable stability and catalytic efficiency across a broad range of temperatures, pH levels, and industrial conditions, making them ideal for diverse industrial applications. Get more details about What makes Aspergillus oryzae enzymes effective under industrial conditions Can Aspergillus oryzae help reduce environmental pollution? Yes, its ability to efficiently break down organic wastes reduces waste volume and facilitates the recycling of nutrients, significantly contributing to eco-friendly waste management and reducing environmental pollution. Get full information here about how Aspergillus oryzae help reduce environmental pollution Are there any specific storage requirements for Aspergillus oryzae products? Aspergillus oryzae products should be stored in a cool, dry place below 25°C, away from direct sunlight to preserve enzymatic activity, potency, and overall stability. Sustainability Advantage Related Products Aspergillus niger Cellulomonas carate Cellulomonas gelida Cellulomonas uda More Products Resources Read all
- Probiotics | Microbial Species | Indogulf BioA
Saccharomyces boulardii is a probiotic yeast that helps maintain gut health and prevents antibiotic-associated diarrhea, promoting digestive balance. < Microbial Species Saccharomyces boulardii Saccharomyces boulardii is a probiotic yeast that helps maintain gut health and prevents antibiotic-associated diarrhea, promoting digestive balance. Strength 1 x 10⁸ CFU per gram / 1 x 10⁹ CFU per gram / 1 x 10¹⁰ CFU per gram Product Enquiry Buy this species Download Brochure Benefits Antimicrobial Properties It inhibits the growth of harmful bacteria and pathogens, contributing to a healthier gut environment and supporting gut health. Support During Antibiotic Use It helps prevent antibiotic-associated diarrhea, promoting gut health during and after antibiotic treatments for optimal recovery. Immune System Enhancement This strain boosts immune function by stimulating the production of antibodies and enhancing the body's defenses against various infections. Digestive Health Support This probiotic yeast helps maintain gut balance, alleviating symptoms of diarrhea and promoting overall digestive comfort and well-being. Dosage & Application Additional Info Scientific References Mode of Action Sustainability Advantage FAQ Scientific References Content coming soon! Mode of Action Content coming soon! Additional Info Key Features All microbial strains are characterized using 16S rDNA. All products are non-GMO. No animal-derived materials are used. The typical shelf life is 2 years. All strains are screened in-house using high-throughput screening methods. We can customize manufacturing based on the required strength and dosage. High-resilience strains Stable under a wide pH range Stable under a broad temperature range Stable in the presence of bile salts and acids Do not show antibiotic resistance Packaging Material The product is packaged in a multi-layer, ultra-high barrier foil that is heat-sealed and placed inside a cardboard shipper or plastic drum. Shipping Shipping is available worldwide. Probiotic packages are typically transported in insulated Styrofoam shippers with dry ice to avoid exposure to extreme high temperatures during transit. Support Documentation Certificate of Analysis (COA) Specifications Material Safety Data Sheets (MSDS) Stability studies (18 months) Certifications ISO 9001 ISO 22000 HACCP Halal and Kosher Certification (for Lactobacillus strains) FSSAI Dosage & Application Contact us for more details FAQ Content coming soon! Sustainability Advantage Related Products Bifidobacterium animalis Bifidobacterium bifidum Bifidobacterium breve Bifidobacterium infantis Bifidobacterium longum Clostridium butyricum Lactobacillus acidophilus Lactobacillus bulgaricus More Products Resources Read all
- Bioremediation | Microbial Species | Indogulf BioA
Flavobacterium oceanosedimentum is a marine bacterium commonly found in ocean sediments, where it plays a critical role in nutrient cycling and organic matter decomposition. This bacterium degrades complex organic materials, contributing to the recycling of nutrients essential for marine ecosystem health. Additionally, F. oceanosedimentum demonstrates potential in bioremediation, particularly in degrading hydrocarbons and other pollutants in marine environments. Its metabolic adaptability and ability to thrive in challenging sediment conditions make it a valuable organism for maintaining ecological balance and supporting sustainable marine resource management. < Microbial Species Flavobacter oceanosedimentum Flavobacterium oceanosedimentum is a marine bacterium commonly found in ocean sediments, where it plays a critical role in nutrient cycling and organic matter decomposition. This bacterium degrades complex organic materials, contributing to the recycling of nutrients essential for marine ecosystem health. Additionally, F. oceanosedimentum demonstrates potential in bioremediation, particularly in degrading hydrocarbons and other pollutants in marine environments. Its metabolic adaptability and ability to thrive in challenging sediment conditions make it a valuable organism for maintaining ecological balance and supporting sustainable marine resource management. Strength 1 x 10⁸ CFU per gram / 1 x 10⁹ CFU per gram / 1 x 10¹⁰ CFU per gram Product Enquiry Buy this species Download Brochure Benefits Nutrient Cycling Contributes to nutrient cycling in marine ecosystems, supporting the health of aquatic life. Hydrocarbon Degradation Capable of degrading hydrocarbons, making it valuable for addressing oil spills and related pollution. Marine Pollutant Degradation Effectively breaks down organic pollutants in marine environments, aiding in ocean cleanup efforts. Sediment Bioremediation Enhances the degradation of contaminants in ocean sediments, promoting ecosystem restoration. Dosage & Application Additional Info Scientific References Mode of Action Sustainability Advantage FAQ Scientific References Content coming soon! Mode of Action Content coming soon! Additional Info Contact us for more details Dosage & Application Contact us for more details FAQ Content coming soon! Sustainability Advantage Related Products Saccharomyces cerevisiae Bacillus polymyxa Thiobacillus novellus Thiobacillus thiooxidans Alcaligenes denitrificans Bacillus licheniformis Bacillus macerans Citrobacter braakii More Products Resources Read all
- Neem Powder Manufacturer & Exporter | Soil Fertilizers | Indogulf BioAg
Indogulf BioAg’s Neem Powder: 100% organic, effective soil treatment. Enhance plant health with our premium, eco-friendly neem powder. Certified & trusted. < Soil Fertilizers Neem Powder The residue from crushed Neem seed kernels used for oil extraction. It contains high levels of nutrients like NPK, nortriterpenoids, and isoprenoids. Product Enquiry Download Brochure Benefits Completely Organic & Biodegradable Derived from the neem tree, it breaks down quickly, enhancing natural plant growth and reducing chemical fertilizer demand by 25 to 30% in the first year. Better Yield Than Conventional Urea Provides superior yields compared to urea while enriching soil quality and maintaining soil fertility. Rich Source of NPK and Micro Nutrients Contains essential nutrients and micro nutrients that enhance soil quality and increase humus content, ideal for improving low organic matter soils. Nematode Prevention Controls a broad spectrum of nematodes and soil pests, promoting nutrient absorption and improving crop yields. Dosage & Application Kit Contents Composition Key Benefits FAQ Additional Info Dosage & Application Neem Powder is applied when preparing your soil for sowing. Plough the soil deeply and mix the Neem Powder thoroughly during this process. This method will yield better results with your harvest. Neem Powder works as both an organic fertilizer and a natural pesticide. If you are transitioning from chemical fertilizer to Neem Powder, apply both over time. Gradually reduce the amount of chemical fertilizer until you are using only Neem Powder. Water the plants after applying Neem Powder to help the nutrients get well absorbed into the soil. Additional Info Shelf Life & Packaging: Storage: Store in a cool, dry place at room temperature Shelf Life: 24 months from the date of manufacture at room temperature Packaging: 1 kg FAQ Content coming soon! Kit Contents Content coming soon! Composition Content coming soon! Key Benefits Content coming soon! Related Products Bio-Manna Bio-Manure Fermogreen Revive Bio More Products Resources Read all
- Blast Manufacturer & Exporter | Disease Management | Rice Protect Kit | Crop Kits | Indogulf BioAg
Indogulf BioAg's Rice Protect Kit: Effective Blast Disease Protection. Manufacturer & Exporter of high-quality agricultural solutions. Order now! < Crop Kits Disease Management | Blast Blast, caused by Pyricularia fungi, leads to elliptical lesions with gray centers and dark borders on leaves, nodes, and panicles. Management involves planting resistant varieties, applying fungicides preventively, practicing crop rotation, and optimizing nutrition. Product Enquiry Download Brochure Management Biological Control FAQ Additional Info FAQ Content coming soon! Management Avoid heavy doses of nitrogen fertilizers; use only recommended doses. Use resistant varieties. Biological Control Use our Consortium of B. subtilis and Pseudomonas fluorescens at 1 kg per acre, diluted in 200 L of water using a high-volume power sprayer. Additional Info Shelf Life & Packaging: Storage: Store in a cool, dry place at room temperature Shelf Life: 24 months from the date of manufacture at room temperature Packaging: 1 kg Disease Management Bacterial Blight Blast Brown Spot Sheath Blight Udbatta Disease Insect Pest Management Army Worms Case Worm Gundhi Bug Leaf Folders Plant Hopper Rice Hispa Root Knot Nematodes Stem Borers Resources Read all
- Arbuscular Mycorrhizal Fungi | Trusted Manufacturer & Exporter | Indogulf BioAg
Looking for mycorrhizal fungi products supplier & manufacturer company in USA? Stop Searching.. Contact +1 437 774 3831 or send email biosolutions@indogulfgroup.com Arbuscular Mycorrhizal Fungi | Trusted Manufacturer & Exporter Even though this idea could seem counter-intuitive, the truth is that the radicular system of a healthy plant does not end with its roots. Not with its own roots, at least. Beyond the roots of the plant itself, a network of fungi expands and brings from the deepest parts of the soil all of the necessary nutrients for the plant’s tasks of producing food and sustaining itself. This type of fungi is called mycorrhizal fungi, from the Greek words ‘mýkes’ and ‘rhiza’; ‘fungus’ and ‘root’ respectively, and these mycorrhizal fungi and plants maintain a mutualistic relationship that goes back millions of years. A symbiotic association between mycorrhiza fungi liquid and plants is established at the root level. To allow two-way nutrition exchange, these mycorrhiza liquids envelop and, in some cases, penetrate the structure of plant roots. Arbuscular mycorrhizal fungi use their mycelium to expand the roots of the plants they interact with, making it easier for them to obtain nutrients, minerals, and water from a greater distance. Photosynthesized sugars are given to the fungus by the mycorrhizal plant in exchange. Some arbuscular mycorrhizal fungi examples are ectomycorrhiza (the fungi responsible for a lot of the mushrooms that can be found in a forest), orchid mycorrhiza (those help orchids and similar plants obtain nutrients from the air), and arbuscular mycorrhiza. Arbuscular mycorrhizal is the most widespread type, occurring in over 85% of all plant families and throughout most crop species. What are the benefits of mycorrhizal associations? Extending the reach of the plant’s roots (often doubling and triplicating them, under favorable conditions) thus increasing not only the depth they can reach but also the amount of surface covered by root mass. Stimulating the absorption of all important nutrients (nitrogen, potassium, iron, manganese, magnesium, copper, zinc, boron, sulphur and molybdenum) by enhancing their availability. Particularly improving the rate of uptake and mobilization of phosphate across all crops, thus reducing phosphorus fertilization requirements. Outcompeting harmful pathogens by rapidly colonizing the roots of the plants, creating a protective barrier against root diseases. Mycorrhizal soil is much harder for pests to colonize, simply because there’s no space for them. Generating an immune response in the plant that, while not killing mycorrhizal fungi, increases the resistance of the plant to future fungal diseases, thus serving as something akin to a ‘plant vaccine’. Producing chemical compounds that attract pest predators when a plant is under attack by pests, mirroring the processes that the plant uses to produce such compounds and boosting predator attraction. Dramatically increasing plant resistance to changing climate and soil conditions such as drought, heat, and even salinity increase. Water absorption, in particular, is enhanced by the mycelia of mycorrhizal fungi serving as root hairs for this purpose. Increasing the overall yield of your plants, by the combined functions of improved nutrient and water absorption and increased resistance to disease and climate conditions. Reducing soil erosion through the production of glomalin by the mycorrhizal fungi, which serves as a binding agent that improves soil structure and increases carbon content. When applied to soil mycorrhizal fungi will produce this protein to coat their hyphae, beneficially releasing it into the ground when they die. A case in practice: mycorrhizal inoculation in corn crops For a simple answer to the question of what are mycorrhizal fungi (and, above all, why do they matter), in the image at left it is possible to see a graphic depiction of how well corn responds to a mycorrhizal fungi inoculation. Arbuscular mycorrhizal fungi grow from within the cells of the roots themselves, serving as ‘branches’ for the expansion of the root system. The fungi associate themselves with the cellular structure of the roots, and begin expanding their hyphae through the soil, bringing nutrients and water to the plant and increasing their reach as their plant host grows stronger and larger. This increases the efficiency with which the plant absorbs the nutrients present in the soil, reducing nutrient runoff and fertilization requirements, as well as improving resistance to drought and disease; ultimately increasing yields and overall plant health. Methods of application of mycorrhizal fungi: The following table provides a basis for how to use arbuscular mycorrhizal fungi in different scenarios, detailing, in particular, the doses required according to each method and to the type of plant being grown (annuals vs. perennials): 1. Application by seed dressing: In an appropriate container for the volume of product required, mix the mycorrhizal inoculant with crude sugar at a proportion of two parts of sugar for one part of mycorrhizal inoculant (for 20-100 kilograms of seed, 100 grams of sugar per 50 grams of mycorrhizal inoculant) insufficient water to make a slurry. Use this liquid preparation to coat the seeds, and allow them to dry in the shade before sowing, casting or dibbling them in the field. Do not store the coated seeds for more than 24 hours before planting. 2. Application directly into soil: Mycorrhizal fungi can be directly applied into the soil through several different strategies, detailed next. Mix the mycorrhizal inoculant with compost at the required dosages, and apply this mixture directly into the soil at the early life stages of the plants, along with any other biofertilizers that may be used. Mix the mycorrhizal inoculant with water at the required dosages, and apply this mixture directly into the soil at the early life stages of the plants, along with any other biofertilizers that may be used. Apply the mycorrhizal inoculant mixed with water under a drip irrigation scheme, filtering out the solution before adding it to the drip tank if any insoluble particles are noticed during its preparation. Use mycorrhizal fungi to boost the continued growth of perennial plants by dissolving the mycorrhizal inoculant in water at the adequate dosage, and drenching the soil where the roots are (for trees, use the drip line as a reference) twice a year. It is recommended to make a first application of this mixture before the onset of the spring, rainfall season or first monsoon, and the second application after the end of the main monsoon, rainfall season or spring season. 3. Application of mycorrhizal fungi as spray. It is recommended that mycorrhizal fungi are applied as close as possible to the roots they will colonize, to ensure maximum effectivity and inoculation rate. If applying as a spray, mix the mycorrhizal liquid at a proportion of 5 milliliters per liter of water, and spray at the drip line of the canopy of the plant. The total volume of the mycorrhizal mixture required may vary depending on the canopy size (and its corresponding drip line). Shelf life and packaging: Shelf life: The product is best before 24 months. Store at room temperature, away from sunlight, heat and humidity. Packaging: The product arrives in a one-kilogram pouch. Relative to plants and their roots, mycorrhizal fungi tend to have a wider temperature tolerance, which may reflect their ability to produce protective compounds. [Read more ] Downloads Product Information Label Information Click here for Product Enquiry Related Articles Let’s take a moment to appreciate the importance of soil inoculants for an organic future It’s no secret that conventionally-cultivated soils tend to become, by themselves, poor. They’re often managed under exploitative... Could mycorrhizal fungi serve as a defense barrier against climate change? The presence of mycorrhizal fungi is a part as vital to sustainable agricultural production as our own intestinal flora is to our nutrition. Mycorrhizal fungi, alongside beneficial bacteria, form the basis of the soil ecosystem and are the first organisms that really break down the nutrients present there into a form that is truly available for plants to use them. But recent research shows that they can also do more: they could be our first line of defense against climate ch
- Bacillus Circulans Manufacturer & Exporter | Plant Growth Promoters | Microbial Species | Indogulf BioA
Bacillus circulans produces indoleacetic acid, solubilizes phosphorus improving absorption, enhances plant growth and yield, safe and eco-friendly. < Microbial Species Bacillus circulans Bacillus circulans produces indoleacetic acid, solubilizes phosphorus improving absorption, enhances plant growth and yield, safe and eco-friendly. Strength 1 x 10⁸ CFU per gram / 1 x 10⁹ CFU per gram / 1 x 10¹⁰ CFU per gram Product Enquiry Buy this species Download Brochure Benefits Enhances nutrient availability in soil Bacillus circulans improves the availability of essential nutrients such as nitrogen, phosphorus, and potassium, promoting better plant growth. Improves phosphorus uptake by plants Facilitates the solubilization of insoluble phosphates in the soil, making phosphorus more accessible to plants for optimal growth and development. Promotes plant growth and development Produces indoleacetic acid (IAA), a plant growth hormone that enhances root and shoot development, resulting in healthier and more vigorous plants. Enhances resistance to abiotic stress Increases plant tolerance to environmental stressors such as drought, salinity, and temperature fluctuations, improving overall plant resilience. Dosage & Application Additional Info Scientific References Mode of Action Sustainability Advantage FAQ Scientific References Content coming soon! Mode of Action Introduction to Bacillus circulans: Nature's Multi-Functional Plant Growth Enhancer Bacillus circulans is a versatile Gram-positive, endospore-forming bacterium that has earned recognition as one of the most effective plant growth-promoting rhizobacteria (PGPR) in sustainable agriculture. Originally described in 1890 by Jordan, this remarkable microorganism demonstrates exceptional abilities in phosphate solubilization, indole-3-acetic acid (IAA) production, and comprehensive plant health enhancement. Recent taxonomic reclassifications have established that Bacillus circulans is now properly classified as Niallia circulans, reflecting advances in bacterial systematics and phylogenetic analysis. mdpi+4 This beneficial bacterium thrives in diverse soil environments and establishes mutually beneficial relationships with numerous crop species, making it an invaluable component of modern biofertilizer formulations. The organism's unique combination of growth-promoting metabolites, stress tolerance capabilities, and environmental safety positions it as a critical tool for addressing agricultural challenges while promoting ecological sustainability. pubmed.ncbi.nlm.nih+1 Characteristics and Biology of Bacillus circulans Taxonomic Classification and Modern Nomenclature Bacillus circulans has undergone significant taxonomic revision in recent years. Comprehensive phylogenetic analyses using 16S rRNA sequencing and comparative genomics have led to its reclassification as Niallia circulans (Jordan 1890) Gupta et al. 2020. This reclassification reflects the polyphyletic nature of the original Bacillus genus and efforts to create more accurate taxonomic groupings based on evolutionary relationships. gbif+1 The genus Niallia was established to honor Professor Niall A. Logan of Glasgow Caledonian University for his contributions to Bacillus systematics. Members of this genus are facultatively anaerobic, motile, and produce resistant endospores, with optimal growth temperatures ranging from 30-37°C. wikipedia+1 Morphological and Physiological Features Physical Characteristics: Bacillus circulans appears as rod-shaped bacteria measuring approximately 0.5-1.0 × 2.0-5.0 micrometers with rounded ends. The bacteria are motile via peritrichous flagella and form characteristic circular colonies with entire margins on standard growth media. semanticscholar Endospore Formation: Like other Bacillus species, Bacillus circulans produces highly resistant endospores that enable survival under extreme environmental conditions including heat, desiccation, radiation, and chemical stress. This spore-forming capability is crucial for maintaining viability during storage and application in agricultural systems. mdpi+1 Growth Requirements: The bacterium demonstrates remarkable adaptability to various pH levels (5.5-9.0), temperatures (15-45°C), and nutrient conditions. This physiological flexibility enables effective colonization across diverse soil types and climatic conditions. pmc.ncbi.nlm.nih+1 Metabolic Versatility and Enzyme Production Bacillus circulans produces an impressive array of extracellular enzymes that contribute to its agricultural and industrial significance: kasetsartjournal.ku+1 β-Mannanase Production: The bacterium produces thermostable β-mannanases used in biobleaching, coffee processing, animal feed improvement, and bioethanol production. These enzymes hydrolyze β-1,4-mannosidic linkages in mannan-based polysaccharides, generating valuable manno-oligosaccharides. kasetsartjournal.ku β-Galactosidase Activity: Bacillus circulans produces β-galactosidase enzymes used industrially for galactooligosaccharide (GOS) production from lactose. These prebiotic compounds have significant applications in food and pharmaceutical industries. pmc.ncbi.nlm.nih Chitinase and Cellulase Production: The organism secretes various polysaccharide-degrading enzymes including chitinases and cellulases, which contribute to organic matter decomposition and nutrient cycling in soil systems. mdpi+1 Additional Info Recommended Crops: Tomato, Banana, Rice Compatibility: Compatible with Bio Pesticides, Bio Fertilizers, and Plant growth hormones but not with chemical fertilizers and chemical pesticides. Shelf Life: Stable within 1 year from the date of manufacturing. Packing: We offer tailor-made packaging as per customers' requirements. Dosage & Application Wettable Powder: 1 x 10⁸ CFU per gram Foliar Application 1 Acre dose: 3-5 kg 1 Ha dose: 7.5 - 12.5 kg Soil Application (Soil drench or Drip irrigation) 1 Acre dose: 3-5 kg 1 Ha dose: 7.5 - 12.5 kg Soil Application (Soil drench or Drip irrigation) for Long duration crops / Orchards / Perennials 1 Acre dose: 3-5 kg 1 Ha dose: 7.5 - 12.5 kg Apply 2 times in 1 Year: Before onset of monsoon and after monsoon Seed Dressing 1 Kg seed: 10g Bacillus Circulans + 10g crude sugar Foliar Application for Long duration crops / Orchards / Perennials 1 Acre dose: 3-5 kg 1 Ha dose: 7.5 - 12.5 kg Apply 2 times in 1 Year: Before onset of monsoon and after monsoon Soluble Powder: 1 x 10⁹ CFU per gram Foliar Application 1 Acre dose: 1 kg 1 Ha dose: 2.5 kg Soil Application (Soil drench or Drip irrigation) 1 Acre dose: 1 kg 1 Ha dose: 2.5 kg Soil Application (Soil drench or Drip irrigation) for Long duration crops / Orchards / Perennials 1 Acre dose: 1 kg 1 Ha dose: 2.5 kg Apply 2 times in 1 Year: Before onset of monsoon and after monsoon Seed Dressing 1 Kg seed: 10g Bacillus Circulans + 10g crude sugar Foliar Application for Long duration crops / Orchards / Perennials 1 Acre dose: 1 kg 1 Ha dose: 2.5 kg Apply 2 times in 1 Year: Before onset of monsoon and after monsoon Seed Dressing Method Mix Bacillus Circulans with crude sugar in sufficient water to make a slurry. Coat seeds and dry in shade before sowing / broadcasting / dibbling in the field. Do not store treated / coated seeds for more than 24 hours. Soil Application Method: Mix at recommended doses with compost and apply at early life stages of crop along with other biofertilizers. Mix Bacillus Circulans at recommended doses in sufficient water and drench soil at early leaf stage / 2-4 leaf stage / early crop life cycle. Drip Irrigation: If there are insoluble particles, filter the solution and add it to the drip tank. For long duration crops / Perennial / Orchard crops: Dissolve Bacillus Circulans at recommended doses in sufficient water and apply as a drenching spray near the root zone twice a year. First application should be before the onset of the main monsoon / rainfall / spring season, and the second application after the main monsoon / rainfall / autumn / fall season. Foliar Application Method Apply foliar application at early disease incidence. Conduct 1-2 follow-up sprays at weekly intervals. Mix Bacillus Circulans at recommended doses in sufficient water and spray on foliage. Apply twice a year for long duration crops. First application should be before the onset of the main monsoon / rainfall / spring season, and the second application after the main monsoon / rainfall / autumn / fall season. Note: Do not store Bacillus Circulans solution for more than 24 hours after mixing in water. FAQ General Biology and Classification What is the current scientific name for Bacillus circulans? The organism is now properly classified as Niallia circulans (Jordan 1890) Gupta et al. 2020, following comprehensive phylogenetic analyses that led to taxonomic reclassification. However, it remains widely known in agricultural applications as Bacillus circulans. gbif+1 How does Bacillus circulans differ from Bacillus cereus? While both are spore-forming bacteria, Bacillus circulans (now Niallia circulans) is phylogenetically distinct from Bacillus cereus. Bacillus cereus belongs to the cereus group and can cause food poisoning, while Bacillus circulans is non-pathogenic and beneficial for plant growth. The two species differ significantly in their toxin production, metabolic capabilities, and safety profiles. wikipedia+4 Can Bacillus circulans cause infections in humans? Bacillus circulans is generally considered non-pathogenic to humans. Unlike Bacillus cereus, which can cause gastrointestinal illness, Bacillus circulans has no documented association with human disease when used in agricultural applications. However, as with any bacterial product, proper handling and application guidelines should be followed. mdpi Agricultural Applications and Effectiveness Which crops benefit most from Bacillus circulans application? Bacillus circulans is particularly effective for tomatoes, bananas, and rice, as specified in product recommendations. However, research shows benefits across diverse crops including cereals, vegetables, and fruits, especially in phosphorus-deficient soils or under stress conditions. mdpi+2 How quickly can farmers expect results from Bacillus circulans? Initial benefits typically become visible within 2-3 weeks as improved root development and enhanced nutrient uptake. Phosphate solubilization effects can be observed within days of application, while maximum growth promotion benefits develop over 6-8 weeks as bacterial populations establish in the rhizosphere. pubmed.ncbi.nlm.nih Can Bacillus circulans replace chemical fertilizers completely? While Bacillus circulans significantly enhances nutrient availability and can reduce fertilizer requirements by up to 25%, it works best as part of an integrated nutrient management system. Complete replacement of chemical fertilizers may be possible in organic systems with adequate organic matter and proper management practices. ojs.revistacontribuciones Safety and Compatibility Is Bacillus circulans safe for organic farming? Yes, Bacillus circulans is completely suitable for organic farming systems as it is a naturally occurring, non-GMO bacterium that enhances soil health and plant nutrition through biological processes. indogulfbioag+1 What should farmers avoid when using Bacillus circulans? Bacillus circulans is compatible with bio-pesticides, bio-fertilizers, and plant growth hormones but should not be applied simultaneously with chemical fertilizers or pesticides that may harm bacterial viability. Avoid storage of prepared solutions for more than 24 hours. indogulfbioag How should Bacillus circulans products be stored? Store products in cool, dry conditions away from direct sunlight and extreme temperatures. The spore-forming nature of Bacillus circulans allows products to maintain stability for up to one year from manufacture date when stored properly. indogulfbioag Technical and Application Questions What is the optimal application method for Bacillus circulans? Application methods include seed dressing (10g per kg seeds), soil application (3-5 kg per hectare), and foliar spray. For long-duration crops and orchards, apply twice yearly before and after monsoon seasons for optimal results. indogulfbioag Can Bacillus circulans be used in hydroponic systems? While traditionally used in soil-based systems, Bacillus circulans can potentially benefit hydroponic cultivation through its phosphate-solubilizing activity and plant hormone production, though specific formulations for soilless systems may require development. How does soil pH affect Bacillus circulans effectiveness? Bacillus circulans functions effectively across a wide pH range (5.5-9.0) but performs optimally in slightly acidic to neutral soils. Its acid-producing activity helps optimize soil conditions for nutrient availability. pmc.ncbi.nlm.nih Sustainability Advantage Related Products Bacillus amyloliquefaciens Bacillus azotoformans Bacillus pumilus Pseudomonas fluorescens Pseudomonas putida Rhodococcus terrae Vesicular arbuscular mycorrhiza Williopsis saturnus More Products Resources Read all
- Paenibacillus Azotofixans Manufacturer & Exporter | Nitrogen Fixing Bacteria | Microbial Species | Indogulf BioA
Paenibacillus azotofixans: Utilized in agricultural practices to promote plant growth by fixing atmospheric nitrogen, thus improving soil fertility, especially in various crop fields. < Microbial Species Paenibacillus azotofixans Paenibacillus azotofixans: Utilized in agricultural practices to promote plant growth by fixing atmospheric nitrogen, thus improving soil fertility, especially in various crop fields. Strength 1 x 10⁸ CFU per gram / 1 x 10⁹ CFU per gram / 1 x 10¹⁰ CFU per gram Product Enquiry Buy this species Download Brochure Benefits Nitrogen Fixation Paenibacillus azotofixans fixes atmospheric nitrogen into ammonia, which enhances nitrogen availability for plants, supporting their growth and development. Plant Growth Promotion Paenibacillus azotofixans produces phytohormones like auxins and cytokinins, which stimulate root growth and increase the efficiency of nutrient and water uptake. Disease Suppression It exhibits antagonistic activity against various plant pathogens, helping to suppress diseases and enhance plant health through competition and antibiotic production. Phosphate Solubilization It solubilizes phosphate in the soil, making it more accessible to plants, which improves their phosphorus uptake and overall nutrient status. Dosage & Application Additional Info Scientific References Mode of Action Sustainability Advantage FAQ Scientific References Molecular Biology and Genetics Genome-Scale Studies: Comprehensive transcriptome analysis of nitrogen fixation in Paenibacillus species has identified over 9,000 differentially expressed genes involved in nitrogen metabolism, energy production, and stress response. These studies provide detailed insights into the molecular mechanisms underlying nitrogen fixation efficiency. biomedcentral Phylogenetic Analysis: Molecular phylogenetic studies based on nifH gene sequences demonstrate that Paenibacillus azotofixans nitrogen-fixing genes cluster with cyanobacterial and archaeal nitrogenases, suggesting ancient evolutionary origins and potential for high activity. journals.asm Regulatory Mechanisms: Advanced molecular studies have elucidated complex regulatory networks involving GlnR, AdeR, and other transcriptional regulators that control nitrogen fixation in response to environmental conditions. microbialcellfactories.biomedcentral+1 Field Performance and Agricultural Applications Multi-Location Trials: Extensive field trials across different climatic zones and soil types consistently demonstrate the effectiveness of Paenibacillus azotofixans for enhancing crop productivity. These studies provide robust evidence for the bacterium's agricultural value under diverse conditions. pmc.ncbi.nlm.nih+1 Long-Term Sustainability: Research demonstrates that repeated application of Paenibacillus azotofixans maintains soil health and fertility without negative environmental impacts. Long-term studies show sustained benefits over multiple growing seasons. pmc.ncbi.nlm.nih Economic Analysis: Cost-benefit analyses demonstrate positive returns on investment from Paenibacillus azotofixans applications, with reduced fertilizer costs offsetting inoculation expenses while providing additional yield benefits. cropj Mode of Action Nitrogen Fixation Biochemistry Paenibacillus azotofixans employs a highly regulated nitrogenase system consisting of multiple enzyme complexes that work together to reduce atmospheric nitrogen: journals.asm+1 Oxygen Sensitivity Management: As an obligate anaerobe process, nitrogen fixation by nitrogenase requires oxygen-free conditions. Paenibacillus azotofixans creates localized anaerobic microenvironments through rapid oxygen consumption and biofilm formation. biomedcentral Energy Requirements: The nitrogen fixation process requires substantial ATP input (16 molecules of ATP per molecule of N₂ fixed). Paenibacillus azotofixans meets this energy demand through efficient carbohydrate metabolism and optimized electron transport chains. biomedcentral Metal Cofactor Utilization: The nitrogenase enzyme complex requires molybdenum, iron, and sulfur cofactors. Paenibacillus azotofixans possesses specialized transport systems for acquiring and concentrating these essential metals. biomedcentral Metabolic Integration and Regulation Ammonium Tolerance Mechanisms: Recent research has revealed that certain Paenibacillus species can overcome ammonium inhibition of nitrogen fixation through alanine dehydrogenase (ADH) activity. This mechanism allows continued nitrogen fixation even in soils with moderate nitrogen availability. microbialcellfactories.biomedcentral Carbon-Nitrogen Balance: The bacterium maintains optimal carbon-nitrogen ratios through sophisticated regulatory networks that coordinate nitrogen fixation with carbon metabolism. This integration ensures efficient resource utilization and sustained bacterial activity. journals.asm Stress Response Systems: Paenibacillus azotofixans possesses multiple stress response mechanisms that maintain nitrogen fixation activity under challenging environmental conditions including drought, temperature extremes, and pH variations. microbialcellfactories.biomedcentral Applications in Biofertilizers and Soil Health Management Commercial Biofertilizer Formulations Paenibacillus azotofixans serves as a key component in advanced biofertilizer formulations designed for various agricultural applications: indogulfbioag+1 Multi-Strain Consortiums: Commercial products often combine Paenibacillus azotofixans with complementary bacteria such as phosphorus-solubilizing bacteria and biocontrol agents to provide comprehensive plant nutrition and protection. indogulfbioag Crop-Specific Formulations: Different application methods and strain combinations are optimized for specific crops and growing conditions. Soybean formulations may emphasize nitrogen fixation, while vegetable applications focus on rapid establishment and growth promotion. cropj Delivery Systems: Paenibacillus azotofixans can be formulated for seed treatment, soil application, or irrigation system delivery, providing flexibility for different farming operations. indogulfbioag Integration with Sustainable Farming Practices Organic Agriculture: As a naturally occurring, non-GMO bacterium, Paenibacillus azotofixans is approved for organic farming systems and supports organic certification requirements. indogulfbioag Precision Agriculture: The bacterium can be integrated into precision farming systems where GPS-guided application ensures optimal placement and dosing based on field-specific soil conditions and crop requirements. Conservation Agriculture: Paenibacillus azotofixans supports no-till and reduced-tillage farming systems by maintaining soil biological activity and nitrogen availability without mechanical soil disturbance. Paenibacillus Species Diversity and Agricultural Significance The Broader Paenibacillus Genus The Paenibacillus species represent one of the most diverse bacterial genera in soil ecosystems, with over 211 described species exhibiting remarkable genetic and phenotypic diversity. This diversity reflects extensive horizontal gene transfer and adaptive evolution that has enabled Paenibacillus species to colonize diverse environmental niches. pmc.ncbi.nlm.nih+1 Genomic Diversity: Comparative genomic analyses reveal that Paenibacillus species possess highly variable genome sizes ranging from 3.9 to 10.4 megabases, with extensive variation in gene content even within species. This genomic plasticity underlies the genus's exceptional environmental adaptability. nature Metabolic Versatility: Paenibacillus species demonstrate remarkable metabolic diversity, with different species specialized for various functions including nitrogen fixation, phosphate solubilization, biocontrol, and organic matter decomposition. This metabolic diversity makes them valuable for diverse agricultural applications. nature Nitrogen-Fixing Paenibacillus Species Multiple Paenibacillus species possess nitrogen-fixing capabilities, each adapted to specific environmental conditions and plant associations: frontiersin+1 Paenibacillus polymyxa: Perhaps the most extensively studied species, demonstrating nitrogen fixation, biocontrol activity, and plant growth promotion across numerous crop species. pmc.ncbi.nlm.nih+1 Paenibacillus borealis: Isolated from forest humus, this species contributes to nitrogen cycling in forest ecosystems and demonstrates potential for forestry applications. microbiologyresearch Paenibacillus graminis: Associated with grass rhizospheres, this species enhances nitrogen availability in forage and turf systems. frontiersin Additional Info Incomplete Section Finalization Paenibacillus azotofixans is recognized for its agricultural significance as a potent nitrogen fixer and plant growth promoter. Modern molecular biology and field-scale studies have validated its benefits for crop nutrition, environmental sustainability, and cost-effectiveness. The bacterium’s versatility and resilience are supported by its diverse regulatory, metabolic, and stress response mechanisms, which make it compatible across a wide range of soil conditions and crop systems. Laboratory Contaminant Significance Paenibacillus species are widely distributed in natural and built environments, including soil, water, and air. Their ability to form spores and survive harsh conditions means they are frequent laboratory contaminants. In clinical and research laboratories, Paenibacillus can be isolated from surfaces, air, gloves, and sample materials—often as part of sterility testing. Several species, including Paenibacillus contaminans, have been specifically described as contaminants during laboratory plate handling. This is particularly relevant in low-biomass environments, as modern sequencing or culture approaches can easily detect spores or cells introduced during sample processing or from ambient air. The high occurrence of Paenibacillus as a contaminant can result in false-positive results, especially in blood cultures, sterile fluids, or low-biomass samples. Proper sample collection, rigorous sterilization, and careful interpretation of culture results are imperative. Contaminants are often identified retrospectively by phylogenetic and phenotypic analysis and may comprise the majority of positive cultures unless clear clinical evidence of infection is present. pmc.ncbi.nlm.nih+3 Human Pathogenicity Paenibacillus species are generally regarded as environmental and plant-associated bacteria. However, accumulating evidence shows that a subset can act as opportunistic pathogens in humans—particularly in immunocompromised individuals, neonates, or following traumatic injuries. Human infections are rare but increasingly described in clinical case reports and systematic reviews. Several species implicated in human disease include P. alvei, P. thiaminolyticus, P. lautus, P. provencensis, and others. Infections range from wound infections, abscesses, ocular infections, sepsis, meningitis, and, rarely, endocarditis. Pathogenicity is driven by several factors: Spore formation and environmental resilience: Spores remain viable on skin surfaces and within hospital environments, making transmission and infection possible under specific conditions. d-nb+1 Virulence factors: Some Paenibacillus possess genes for thiol-activated cytolysins, proteases, biofilm formation, and antimicrobial compound production. journals.plos+3 Antibiotic resistance: Many isolates demonstrate resistance to multiple antibiotics, particularly penicillins, clindamycin, sulfonamides, and sometimes vancomycin, calling for careful susceptibility testing. pure.psu+4 Clinical Management Recommendations Management of Paenibacillus infections hinges on accurate diagnosis and effective antimicrobial therapy. As precaution, clinicians should: Differentiate true infection from contamination: Always correlate positive cultures with clinical signs (fever, leukocytosis, infection at the site), especially when Paenibacillus is isolated from blood, sterile fluids, or deep wounds. pmc.ncbi.nlm.nih+2 Empiric and directed antibiotic therapy: Initial therapy is empiric, but due to variable resistance patterns, therapy should be adjusted based on susceptibility testing. Effective options typically include cefotaxime, ceftriaxone, gentamicin, amikacin, rifampicin, metronidazole, and levofloxacin, while resistance to penicillins, clindamycin, and vancomycin can occur. Trimethoprim-sulfamethoxazole may be used for P. urinalis. droracle+6 Remove or drain infection sources: Surgical removal of infected tissues, foreign bodies, or abscess drainage may be necessary in localized infections. Monitor for complications: Especially in infants, Paenibacillus can cause severe complications like meningitis and hydrocephalus, requiring close monitoring and sometimes neurosurgical intervention. thelancet+2 Follow-up and continuity of care: Persistent infections require long-term medical follow-up and sometimes prolonged antibiotic administration. pmc.ncbi.nlm.nih+1 Current Knowledge of Human Infections Systematic reviews and case series demonstrate that although Paenibacillus species are uncommon human pathogens, the number of species associated with clinical infections is growing. Infection presentations differ notably between adults and infants: Adults: Infections are sporadic, caused by a wide array of species, often present as wound infections, abscesses, or localized sepsis. Central nervous system involvement is rare, and most cases resolve with treatment. pubmed.ncbi.nlm.nih+2 Infants: Neonatal infections are far more severe, especially with P. thiaminolyticus, and often present as sepsis or meningitis with a high risk of cerebral destruction and hydrocephalus. Mortality rates are notable, and survivors often need surgical intervention for neurological sequelae. pmc.ncbi.nlm.nih+3 The overall frequency of infection remains low relative to the ubiquity of the genus, indicating that most isolates are contaminants, but vigilance is still warranted for at-risk populations. Recommended Crops: Cereals, Millets, Pulses, Oilseeds, Fibre Crops, Sugar Crops, Forage Crops, Plantation crops, Vegetables, Fruits, Spices, Flowers, Medicinal crops, Aromatic Crops, Orchards, and Ornamentals. Compatibility: Compatible with Bio Pesticides, Bio Fertilizers, and Plant growth hormones but not with chemical fertilizers and chemical pesticides. Shelf Life: Stable within 1 year from the date of manufacturing. Packing: We offer tailor-made packaging as per customers' requirements. Dosage & Application Seed Coating/Seed Treatment: Coat 1 kg of seeds with a slurry mixture of 10 g of Paenibacillus Azotofixans and 10 g of crude sugar in sufficient water. Dry the coated seeds in shade before sowing or broadcasting in the field. Seedling Treatment: Dip seedlings into a mixture of 100 grams of Paenibacillus Azotofixans with sufficient water. Soil Treatment: Mix 3-5 kg per acre of Paenibacillus Azotofixans with organic manure or fertilizers. Incorporate into the soil during planting or sowing. Irrigation: Mix 3 kg per acre of Paenibacillus Azotofixans in water and apply through drip lines. FAQ What is the significance of Paenibacillus as a potential laboratory contaminant? Answer: Paenibacillus species are among the most frequently isolated laboratory contaminants, especially in low-biomass and sterile sample environments. Their spores persist in air, on surfaces, and even on personal protective equipment, leading to inadvertent contamination of cultures and clinical specimens. Laboratory contaminants can cause diagnostic confusion, particularly when isolated from blood cultures or sterile sites, given the genus’s environmental prevalence. Recognizing Paenibacillus as a contaminant is vital to prevent misdiagnosis, unnecessary antimicrobial therapy, and misleading research conclusions. Rigorous sample handling and critical assessment of laboratory results are essential in distinguishing contamination from true infection. sciencedirect+4 Can Paenibacillus species exhibit pathogenicity in humans? Answer: Although primarily environmental and plant-associated, certain Paenibacillus species can exhibit pathogenicity in humans, particularly in vulnerable populations such as neonates, immunocompromised individuals, or following trauma. Documented infections include sepsis, wound infection, abscesses, meningitis, endocarditis, ocular infections, and rare systemic disease. Species like P. alvei, P. thiaminolyticus, and P. lautus are increasingly identified as clinical pathogens. In neonates, P. thiaminolyticus is notably associated with severe CNS infections. Virulence factors, antibiotic resistance, and spore persistence contribute to pathogenic potential, although true infections remain rare compared to environmental contamination. wwwnc.cdc+9 What are the recommended clinical approaches for managing Paenibacillus infections? Answer: Management is guided by accurate diagnosis and susceptibility-directed antimicrobial therapy. Clinicians should distinguish true infection from laboratory contamination, correlate culture results with clinical findings, and employ targeted treatment. Empiric therapy can include cefotaxime, ceftriaxone, gentamicin, amikacin, levofloxacin, and rifampicin, but resistance to penicillin, clindamycin, vancomycin, and sulfonamides is not uncommon. Susceptibility testing is imperative prior to finalizing antibiotic choice. Additional interventions such as surgical drainage of infected tissues may be necessary. Neonatal and CNS infections require close multidisciplinary management. Long-term monitoring is advised due to the potential for persistent or recurrent infection and post-infectious complications. pmc.ncbi.nlm.nih+7 What is currently known about human infections caused by Paenibacillus species? Answer: Human Paenibacillus infections, while uncommon, are increasingly recognized in pediatric and adult populations. Infections in adults are sporadic and generally mild, presenting as localized wound infection, abscesses, or sepsis, and most affected individuals recover without severe sequelae. Neonatal infections, especially those due to P. thiaminolyticus, are severe and often complicated by brain injury, hydrocephalus, and require surgical intervention, with notable associated mortality. The rise in documented cases reflects improved detection, growing awareness, and advances in microbiological diagnostics. Nonetheless, the majority of clinical isolates are contaminants rather than true pathogens, highlighting the importance of careful clinical interpretation and management. Ongoing research is elucidating new species, virulence mechanisms, and optimized treatment protocols. sciencedirect+9 Sustainability Advantage Related Products Acetobacter xylinum Azospirillum brasilense Azospirillum lipoferum Azospirillum spp. Azotobacter vinelandii Beijerinckia indica Bradyrhizobium elkanii Bradyrhizobium japonicum More Products Resources Read all
- Probiotics | Microbial Species | Indogulf BioA
Bifidobacterium bifidum supports digestive health and helps maintain a balanced gut microbiota for optimal digestion and nutrient absorption. < Microbial Species Bifidobacterium bifidum Bifidobacterium bifidum supports digestive health and helps maintain a balanced gut microbiota for optimal digestion and nutrient absorption. Strength 1 x 10⁸ CFU per gram / 1 x 10⁹ CFU per gram / 1 x 10¹⁰ CFU per gram Product Enquiry Buy this species Download Brochure Benefits Gut Barrier Protection It helps strengthen the gut barrier, reducing intestinal permeability and inflammation, thus supporting overall digestive health and well-being. Immune System Support It boosts the immune system by increasing the production of immune cells and enhancing the body’s ability to fight infections and illnesses. Prebiotic Interaction This strain works synergistically with prebiotics, helping to ferment dietary fibers and promote the growth of beneficial gut bacteria. Digestive Health Enhancement This probiotic supports digestive health by promoting a balanced gut microbiota, alleviating symptoms of constipation and diarrhea, and enhancing overall gut function. Dosage & Application Additional Info Scientific References Mode of Action Sustainability Advantage FAQ Scientific References Content coming soon! Mode of Action Content coming soon! Additional Info Key Features All microbial strains are characterized using 16S rDNA. All products are non-GMO. No animal-derived materials are used. The typical shelf life is 2 years. All strains are screened in-house using high-throughput screening methods. We can customize manufacturing based on the required strength and dosage. High-resilience strains Stable under a wide pH range Stable under a broad temperature range Stable in the presence of bile salts and acids Do not show antibiotic resistance Packaging Material The product is packaged in a multi-layer, ultra-high barrier foil that is heat-sealed and placed inside a cardboard shipper or plastic drum. Shipping Shipping is available worldwide. Probiotic packages are typically transported in insulated Styrofoam shippers with dry ice to avoid exposure to extreme high temperatures during transit. Support Documentation Certificate of Analysis (COA) Specifications Material Safety Data Sheets (MSDS) Stability studies (18 months) Certifications ISO 9001 ISO 22000 HACCP Halal and Kosher Certification (for Lactobacillus strains) FSSAI Dosage & Application Contact us for more details FAQ Content coming soon! Sustainability Advantage Related Products Bifidobacterium animalis Bifidobacterium breve Bifidobacterium infantis Bifidobacterium longum Clostridium butyricum Lactobacillus acidophilus Lactobacillus bulgaricus Lactobacillus casei More Products Resources Read all









